A novel catalytic approach for the synthesis of symmetric and asymmetric azines has been developed. The environmentally benign protocol was achieved via condensation 1-[(2-thienyl)ethylidene]hydrazine (1) with different aromatic aldehydes 2a–h acetyl heterocyclic compounds (4, 6, 8, 10, 12) in presence cellulose sulfuric acid (CSA) as green catalyst. These procedures offer an interesting method...