Long chain fatty acids have been found to exhibit both inhibitory and stimulatory effects on the growth of tubercle bacilli and of a certain unidentified micrococcus culture. The toxicity of the fatty acids was much reduced or abolished by (a) esterification, even when the resulting product was a water-soluble ester, and (b) addition of crystalline serum albumin to the culture medium; other pro...

Comparison of the lipid composition between members of the Mycoplasmatales reveals a striking diversity of lipid structures, not only between the six genera but among species within the same genus. This is in contrast to nearly all other bacterial groups in which members of the same genus possess essentially the same lipids. There are in fact more similarities between lipids of a given species ...

Biogeosciences Discussions This discussion paper is/has been under review for the journal Biogeosciences (BG). Please refer to the corresponding final paper in BG if available. Abstract The lipid content of seven samples of sinking particles collected with sediment traps moored at ∼100 m depth in summer and fall across the Canadian Beaufort Shelf (Arc-tic Ocean) was investigated. Our main goal ...

Work, which was begun in the author's laboratory in 1948, on the chemistry of various lipid fractions of Mycobacteria and other acid-fast micro-organisms, has led to the identification and elucidation of the chemistry of a number of compounds having unusual structures and interesting biological activities. The principal compounds studied are branchedchain high molecular weight fatty acids, gl y...

This protocol describes two similar methods for the extraction and methylation of fatty acids from bacterial cultures. The acid derivatization protocol (Lennen et al., 2013; Bligh and Dyer, 1959) results in the extraction and methylation of all fatty acids, both free and bound, from a bacterial culture, while the base derivatization protocol (Lennen and Pfleger, 2013) captures only bound (phosp...

• The influence of different Household Food Wastes fractions on VFA was investigated. Fractions rich in proteins and starch led to the highest yield (12–15 g/L). cellulose, fibers, sugars showed low production (<2 Metagenomic analysis HFW VFAs conducted. bacterial community compositions profile correlated. This research investigated for first time single (proteins, lipids, starch, fibers sugars...

Liquid-ordered phases are one of two biochemically active membrane states, which until now were thought to be a unique consequence of the interactions between eukaryotic membrane lipids. The formation of a liquid-ordered phase depends crucially on the ordering properties of sterols. However, it is not known whether this capacity exists in organisms that lack sterols, such as bacteria. We show t...

Lipids synthesized on the skin are crucial to antimicrobial barrier. Skin lipids also facilitate survival of lipophilic commensals in an otherwise dry and acidic ecological landscape. Skin-specific stearoyl-Coenzyme A desaturase 1 (SCD1) knockout mice known have dry, inflamed skin, with sebocyte atrophy decreased synthesis monounsaturated fatty acids, triglycerides, wax diesters. Characterizing...

Bacterial membranes are highly organized, containing specific microdomains that facilitate distinct protein and lipid assemblies. Evidence suggests that cardiolipin molecules segregate into such microdomains, probably conferring a negative curvature to the inner plasma membrane during membrane fission upon cell division. 3',6-Dinonyl neamine is an amphiphilic aminoglycoside derivative active ag...

Periodontitis is a chronic inflammatory disease induced by dysbiotic dental biofilms. Management of periodontitis primarily anti-bacterial via mechanical removal bacterial biofilm. The successful resolution requires wound healing and tissue regeneration, which are not always achieved with these traditional methods. discovery specialized pro-resolving mediators (SPMs), class lipid that induce th...