نتایج جستجو برای: bacterial vaccines

تعداد نتایج: 253193  

2012
Joseph Domachowske

Vaccines are among the most effective public health interventions available. Global eradication of smallpox infection, the elimination of polio from the Western hemisphere, and dramatic reductions in diseases like diphtheria, tetanus, pertussis, measles, mumps, rubella, varicella, rotavirus, hepatitis A and B have all been achieved through immunization programs. The public health impact of well...

Journal: :international journal of infection 0
batool sharifi-mood infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran ali khajeh children and adolescents health research center, aliebn-e-abitaleb hospital, zahedan university of medical sciences, zahedan, ir iran maliheh metanat infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran azam rasouli infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran; infectious diseases and tropical medicine research center, zahedan university of medical sciences, boo-ali hospital, zahedan, ir iran. tel: +98-54133228101-2, fax: +98-54133236722

background meningitis is an inflammation of the membranes, which surround the brain and spinal cord. early treatment of bacterial meningitis can prevent serious complications. in the last two decades, three vaccines have been developed against the three main bacterial species implicated in meningitis of children in western countries and vaccine-preventable invasive bacterial meningitis has decr...

2017
Jonnel A. Jaurigue Peter H. Seeberger

Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine development, given the proven success of carbohydrate vaccines to combat bacterial infections. We will review the key components of carbohydra...

Journal: :Cold Spring Harbor perspectives in medicine 2013
Isabel Delany Rino Rappuoli Kate L Seib

Advances in genomics and innovative strategies such as reverse vaccinology have changed the concepts and approaches to vaccine candidate selection and design. Genome mining and blind selection of novel antigens provide a novel route to investigate the mechanisms that underpin pathogenesis. The resulting lists of novel candidates are revealing new aspects of pathogenesis of target organisms, whi...

Maryam Kheirandish Mohammad Reza Aghasadeghi Seyed Davar Siadat

Meningococcal disease remains a significant global public health and is unique among causes of bacterial meningitis and sepsis where it not only causes sporadic disease but also outbreaks. Meningococcal disease has a rapid onset with high mortality. The understanding of immunopathogenesis is crucial for development of novel therapeutic strategies and vaccines designed against meningococcal dise...

2018
Mutsumi Furukawa Hiroshi Yoneyama Eiji Hata Hidetomo Iwano Hidetoshi Higuchi Tasuke Ando Mika Sato Tomohito Hayashi Yoshio Kiku Yuya Nagasawa Kanae Niimi Katsuki Usami Kumiko Ito Kouichi Watanabe Tomonori Nochi Hisashi Aso

Staphylococcus aureus is a major pathogen that causes subclinical mastitis associated with huge economic losses to the dairy industry. A few vaccines for bovine mastitis are available, and they are expected to induce the production of S. aureus-specific antibodies that prevent bacterial adherence to host cells or promote opsonization by phagocytes. However, the efficacy of such vaccines are sti...

Journal: :Clinical microbiology reviews 2010
Matthijs C Brouwer Allan R Tunkel Diederik van de Beek

The epidemiology of bacterial meningitis has changed as a result of the widespread use of conjugate vaccines and preventive antimicrobial treatment of pregnant women. Given the significant morbidity and mortality associated with bacterial meningitis, accurate information is necessary regarding the important etiological agents and populations at risk to ascertain public health measures and ensur...

Journal: :Revue scientifique et technique 2008
G Kurath

Biotechnology has been used extensively in the development of vaccines for aquaculture. Modern molecular methods such as polymerase chain reaction (PCR), cloning and microarray analysis have facilitated antigen discovery, construction of novel candidate vaccines, and assessments of vaccine efficacy, mode of action, and host response. This review focuses on DNA vaccines for finfish to illustrate...

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