نتایج جستجو برای: band heterotopia of brain
تعداد نتایج: 21234613 فیلتر نتایج به سال:
The positioning of neurons in the cerebral cortex is of crucial importance for its function as highlighted by the severe consequences of migrational disorders in patients. Here we show that genetic deletion of the small GTPase RhoA in the developing cerebral cortex results in two migrational disorders: subcortical band heterotopia (SBH), a heterotopic cortex underlying the normotopic cortex, an...
Double intraperitoneal injections of methylazoxymethanol (MAM) in pregnant rats induce developmental brain dysgenesis with nodular heterotopia similar to human periventricular nodular heterotopia (PNH) and composed of hyperexcitable neurons. Here we analyzed the NMDA receptor complex and associated proteins in the heterotopic neurons of 2- to 3-month-old MAM-treated rats by means of a combined ...
Developmental malformations are brain abnormalities that occur during embryogenesis. Neuronal migration disorders, including heterotopic lesions, constitute one type of such abnormalities. The aim of the study was to compare the epileptic clinical patterns of patients with periventricular nodular heterotopia (PNH) (G1) with those affected by subcortical heterotopia (SCH) (G2) looking for differ...
The Schottky barrier heights (SBH) for -Al2O3(0001)/Ni(111) interfaces have been examined using the first-principles pseudopotential method, and compared with our previous results of Al2O3(0001)/Cu(111) interfaces. Configurations with different rigid-body translations parallel to the interface for both the O-terminated and Al-terminated interfaces are examined to clarify the influence of the mi...
This study investigates the incidence of high-salt diet in blood pressures, renal alpha(2)-adrenoceptor subtypes distribution, and gene expression in salt-sensitive (SBH) and salt-resistant (SBN) Sabra rats. Comparisons have been made between SBH and SBN rats submitted to a normal or a high-salt diet for 6 weeks. Only alpha(2)B-adrenoceptors are detected in kidneys of SBH rats, whatever the die...
Maria Daniela D'Agostino,1,2 Andrea Bernasconi,1 Soma Das,5 Alexandre Bastos,1 Rosa M. Valerio,1,10 Andre Palmini,11 Jaderson Costa da Costa,11 Ingrid E. Scheffer,13 Samuel Berkovic,1,13 Renzo Guerrini,14 Charlotte Dravet,15 Jiro Ono,16 GianLuigi Gigli,17 Antonio Federico,18 Fran Booth,4 Bruno Bernardi,19 Lilia Volpi,19 Carlo Alberto Tassinari,19 Mary Anne Guggenheim,6 David H. Ledbetter,5 Jos...
D0-brane gas picture of Schwarzschild black hole (SBH) is considered in the large N regime of Matrix theory. An entropy formula, which reproduces the thermodynamics of SBH in the large N limit for all dimensions (D ≥ 6), is proposed. The equations of states for low temperature are obtained. We also give a proof of the Newton gravitation law between two SBHs, whose masses are not equal. Our resu...
Sequencing by Hybridization (SBH) reconstructs an n-long target DNA sequence from its biochemically determined l-long subsequences. In the standard approach, the length of a uniformly random sequence that can be unambiguously reconstructed is limited to n = O(2(l)) due to repetitive subsequences causing reconstruction degeneracies. We present a modified sequencing method that overcomes this lim...
Malformations of cortical development (MCD) are an important aetiology of localization-related epilepsy. Previous MRI and [11C]flumazenil PET studies have demonstrated widespread structural and neuroreceptor abnormalities beyond the region of MCD that is visually apparent on MRI. We investigated the ability of brain regions affected by MCD to participate in normal cognitive and motor tasks and ...
D0-brane gas picture of Schwarzschild black hole (SBH) is considered in the large N limit of Matrix theory. An entropy formula, which reproduces the thermodynamics of SBH in the large N limit for all dimensions (D ≥ 6), is proposed. The equations of states for low temperature are obtained. We also give a proof of the Newton gravitation law between two SBHs, whose masses are not equal. Our resul...
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