Abstract A 70-year-old man was referred to oral medicine with extensive, painful hyperkeratosis affecting the tongue, buccal mucosa and palate. Medical history included a previous diagnosis of prostate cancer. Histology from multiple biopsy specimens showed only hyperparakeratosis acanthosis, no fungi or dysplasia. Owing absence inflammation, pain treated as neuropathic. The patient then develo...

Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is a hereditary condition characterized by a wide range of developmental abnormalities and a predisposition to neoplasms. The estimated prevalence varies from 1/57,000 to 1/256,000, with a male-to-female ratio of 1:1. Main clinical manifestations include multiple basal cell carcinomas (BCCs), odontogenic keratocysts of...

Actinic erythema Polymorphous light eruption Tristimulus colorimeter Charles R. Taylor, MD, Instructor in Dermatology, Medical Director of Phototherapy, Massachusetts General Hospital, Bartlett Hall, Room 414, 32 Fruit Street, Boston, MA 02114 (USA) Garigue et al. [1J recently administered routine minimal erythema doses to 72 patients. They then used a tristimulus colorimeter to measure the ery...

A 53-year-old man presented with a 3-day history of bilateral pain in the lower extremities. He also had a 3-month history of thickening and desquamation of skin, with associated itching, and a 5-lb (2.27-kg) weight loss. The skin changes initially appeared on the hands and subsequently became generalized. The patient denied fever, cough, chest pain, dyspnea on exertion, joint pain, and mucosal...

Focal epithelial hyperplasia (FEH) of the oral mucosa occurring in a HIV-infected man is described. Molecular biology disclosed an HPV-32 type in oral lesions. The association of FEH and AIDS is uncommon although many HPV subtypes may manifest during HIV infection. R. Viraben, Service de Dermato-vénéréologie, CHU La Grave, Place Lange, F-31052 Toulouse Cedex (France) D ow nl oa de d by : 54 .7 ...