نتایج جستجو برای: bcg vaccination

تعداد نتایج: 66599  

Journal: :Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2006
Ghamar Taj Khotaei Leyla Sedighipour Fatemeh Fattahi Zahra Pourpak

Bacille Calmette-Guérin (BCG) osteomyelitis is a very rare complication of BCG vaccination. We report a 14-month-old boy who received BCG vaccination at birth. He developed pain and swelling in his left calf at 11 months of age. BCG osteomyelitis was diagnosed in right femur and left tibia. He had no evidence of immunodeficiency. After antituberculous therapy and surgical treatment, the bone le...

Journal: :JCI insight 2017
Melanie A Gasper Anneke C Hesseling Isaac Mohar Landon Myer Tali Azenkot Jo-Ann S Passmore Willem Hanekom Mark F Cotton I Nicholas Crispe Donald L Sodora Heather B Jaspan

BACKGROUND. Bacillus Calmette-Guérin (BCG) vaccine is administered at birth to protect infants against tuberculosis throughout Africa, where most perinatal HIV-1 transmission occurs. We examined whether BCG vaccination alters the levels of activated HIV target T cells in HIV-exposed South African infants. METHODS. HIV-exposed infants were randomized to receive routine (at birth) or delayed (at ...

2018
Elisa Nemes Anneke C Hesseling Michele Tameris Katya Mauff Katrina Downing Humphrey Mulenga Penelope Rose Marieke van der Zalm Sharon Mbaba Danelle Van As Willem A Hanekom Gerhard Walzl Thomas J Scriba Helen McShane Mark Hatherill Charmaine Abrahams Deborah Abrahams Hadn Africa Veronica Baartman Beauty Bavuma Nicole Bilek Natasja Botes Yolande Brown Yolundi Cloete Margareth Damons Ronel De Vos Portia Dlakavu Karen Du Preez Mzwandile Erasmus Claudia Francis Hendrik Geldenhuys Mandy Geldenhuys Katriena Goedeman Sandra Golliath Angelique Hendricks Mouton Christiaan Hopley Ruwijda Jansen Carolynne Jones Alana Keyser Benjamin Kagina Gloria Khomba Fazlin Kola–Cassiem Sandra Kruger Daphne Leukes Loyiso Louw Angelique Luabeya Theresa Maart Lebohang Makhethe Simbarashe Mbabwe Eunice Mtshamba Boniswa Mvinjelwa Lungisa Nkantsu Julia Noble Sizwe Nqweniso Fajwa Opperman Christel Petersen Patiswa Plaatjie Susan Rossouw Roxanne Solomoms Marcia Steyn Liticia Swanepoel Asma Toefy Heidi van Deventer Elma van Rooyen Daphne van Ster Bongiwe Vazana Ashley Veldsman Noncedo Xoyana

Background Vaccination of human immunodeficiency virus (HIV)-infected infants with bacille Calmette-Guérin (BCG) is contraindicated. HIV-exposed newborns need a new tuberculosis vaccination strategy that protects against tuberculosis early in life and avoids the potential risk of BCG disease until after HIV infection has been excluded. Methods This double-blind, randomized, controlled trial c...

Journal: :Indian pediatrics 2008
Priyanka Gupta M M A Faridi Dheeraj Shah Geeta Dev

OBJECTIVE To study local response to BCG vaccination in twin babies and find out the effect of zygosity andchorionicity on BCG uptake. DESIGN Analytical observational study. SETTING Tertiary hospital. METHODS Twin pairs born in the hospital were evaluated for zygosity and chorionicity. BCG vaccination was given within 48 hours of birth to babies >/=33 weeks of gestation and birth weight >...

Journal: :Vaccine 2014
Yu Deng Wei Li Yan Luo Li J Wang Xiao H Xie Jian Luo Zheng X Luo Xiao D Zhao Zhou Fu En M Liu

OBJECTIVE The Mycobacterium bovis Bacillus Calmette-Guerin (BCG) neonatal vaccination inhibits allergy-induced pathologic changes. However, the mechanisms underlying this process are unclear. This study aimed to investigate the role of interferon (IFN)-γ and interleukin (IL)-17 in the protective effects of the BCG neonatal vaccination on allergic pulmonary inflammation and airway hyperresponsiv...

Journal: :Indian pediatrics 1995
S Thora P Rajsekaran B C Chhaparwal

Serum adenosine deaminase (ADA) levels reflect activity of stimulated T lymphocytes and its levels are raised whenever cell mediated immunity is stimulated. One hundred term normal newborns were studied to evaluate effect of BCG vaccination on serum ADA levels. Serum ADA was measured at birth and 6 weeks after BCG vaccination. Only 67 subjects came for follow up after 6 weeks. The levels were 6...

Journal: :The Yale Journal of Biology and Medicine 1953
Russell Miller

BCG VACCINATION. Studies by the WHO Tuberculosis Research Office, Copenhagen. Report prepared under the direction of Lydia B. Edwards and Carroll E. Palmer with the assistance of Knut Magnus. Monograph Series No. 12. Geneva, World Health Organization, 1953. 307 pp. 15/-, $3.00, Sw. fr. 12.This monograph contains the results of an inquiry into the variable factors that affect BCG vaccination. Th...

2000

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

2000

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

2016
Bryan E Hart Sunhee Lee

Buruli ulcer (BU) vaccine design faces similar challenges to those observed during development of prophylactic tuberculosis treatments. Multiple BU vaccine candidates, based upon Mycobacterium bovis BCG, altered Mycobacterium ulcerans (MU) cells, recombinant MU DNA, or MU protein prime-boosts, have shown promise by conferring transient protection to mice against the pathology of MU challenge. R...

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