P reparative chromatography is the dominant purification technique in the production of biological compounds, especially for bioseparations. The column used is central to the performance of the chromatographic step. To ensure robust and reproducible column performance, columns need to be qualified in an acceptable fashion before each use. Some of the critical elements of column qualification in...

The effect of foaming on the performance of 16 mm Pall rings was determined in a 0.15 m distillation column with a ‘bed depth of 1.23 m. The tests were conducted with the methanol/water system at 1.0 bar pressure. A controllable foaming inside the packed bed was generated successfully with the addition of the surfactant, Triton X-100, to the reflux stream. The performance of the packing with an...

Abstract The present study aims at development of a mathematical model for the fixed-bed column adsorption that relates reactor parameters with breakthrough curve. Effects operating like bed height, flow rate, initial adsorbate concentration on were investigated by using various curves. arbitrary constants developed found to be dependent kinetics. proposed showed incredible results (Breakthroug...

Fixed-bed operating experimental column conditions were studied to evaluate the performance of brick from Bangui Region (in Central African Republic), coated with iron oxyhydroxide (ferrihydrite) for removal iron(II) aqueous solution. The prediction theoretical breakthrough profiles using Bohart and Adams sorption model was employed achieve characteristic parameters such as depth exchange zone,...

the continuous filter is a kind of sand filter, which will operate without any interruptions for backwashing and also it accepts high-suspended solid levels in feed stream. fouled sand is continuously removed from the filter bed, washed and recycled back without interruption with filtration process. various samples of water with certain amounts of turbidity enter through a feed pipe and being d...

Leaching occurs in metals recovery, in contaminated soil washing, and in many natural processes, such as fertilizer dissolution and rock weathering. This paper presents a model developed to simulate the transient evolution of the dissolved chemical species in the heap and column isothermal leaching processes. In this model, the solid bed is numerically divided into plane layers; the recovery of...

−To obtain highly purified naphthalene, a column crystallizer was employed and operated in the continuous multistage countercurrent fractional mode. The principles and characteristics of the process are introduced. A large amount of experimental work has been done on the crystallization process in a D=50 mm×1,350 mm column. The effects of operation conditions including the composition of feed, ...

[1] Shallow coastal lagoons are environments where a dynamic equilibrium exists between water quality and seagrass cover. Dense seagrass canopies limit the resuspension of bed sediments thereby creating a clearer water column and a positive feedback for seagrass growth. Positive feedbacks are often associated with the existence of bistable dynamics in ecosystems. For example, a bare and a seagr...

Modeling mass-transfer across the sediment-water interface is a significant issue in environmental hydraulics. In fact diffusional exchanges of solutes between the bed sediment and the overlying water column could greatly affect water quality. Particularly, diffusional flux of dissolved oxygen (DO) towards the bed sediments from the water column could be responsible for low and unacceptable lev...