نتایج جستجو برای: benzofuran derivatives iodine

تعداد نتایج: 127573  

2014
James Herndon Steven Kass

Research in the Herndon group focuses on the discovery of new organotransition metal-based processes for use in organic synthesis. Of specific interest are reactions that transform simple starting materials into complex products in a general, predictable, efficient, and stereoselective manner. Most of our present activity involves exploration of the coupling reaction between Fischer carbene com...

Journal: :Journal of medicinal chemistry 2013
Leonardo Pisani Maria Barletta Ramon Soto-Otero Orazio Nicolotti Estefania Mendez-Alvarez Marco Catto Antonellina Introcaso Angela Stefanachi Saverio Cellamare Cosimo Altomare Angelo Carotti

The use of selective inhibitors of monoamine oxidase A (MAO-A) and B (MAO-B) holds a therapeutic relevance in the treatment of depressive disorders and Parkinson's disease (PD), respectively. Here, the discovery of a new class of compounds acting as monoamine oxidase inhibitors (MAO-Is) and bearing a 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-alkylacetamide skeleton is reported. 6'-Sulfo...

Journal: :Chemical communications 2013
Mekhman S Yusubov Dmitrii Yu Svitich Akira Yoshimura Victor N Nemykin Viktor V Zhdankin

New powerful hypervalent iodine(V) oxidants, tosylate and mesylate derivatives of 2-iodoxybenzoic acid (IBX), were prepared by the reaction of IBX with the corresponding sulfonic acids. Single crystal X-ray crystallography of the diacetate derivative of IBX-tosylate revealed an unusual heptacoordinated iodine geometry without any significant intermolecular secondary interactions.

Journal: :journal of physical and theoretical chemistry 0
farnaz abolfazli- khosroshahi organic chemistry department, faculty of chemistry, tabriz university, tabriz, iran akbar saeidniya organic chemistry department, faculty of chemistry, tabriz university, tabriz, iran

the synthesis and characterization a new derivatives of 2'-iodo-meta terphenyl from the reaction ofexcess aryl-grignard and 2, 6- dichloroiodobenzene with quenching of m-terphenyl-2'-magnesiumbromide by iodine is reported. via the reactions three carbon-carbon bonds are constructed and mterphenylsare obtained in good yields.

Journal: :Anticancer research 2005
Werner Krause Andreas Jordan Regina Scholz José-Luis Martin Jimenez

Four different nitroimidazole derivatives, with up to two iodine atoms on the imidazole ring, were investigated for their radiosensitizing potency under hypoxic conditions, in order to test whether the introduction of iodine atoms increases the radiosensitizing potency of nitroimidazoles. Misonidazole and metronidazole were used as controls. Human colonic adenocarcinoma cells were incubated wit...

Journal: :RSC Advances 2021

The kinetic reaction of the benzofuran–stilbene hybrid compound 5-(2-(2-(4-hydroxyphenyl)benzofuran-5-yl)vinyl)benzene-1,3-diol captures HOO? free radical.

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