Since lysosomes are prone to osmotic lysis, we have examined the correlation between their physical state and sensitivity to osmotic challenge, using agents which modify membrane fluidity. The latency loss of beta-hexosaminidase after an incubation in hypotonic sucrose medium was followed under different conditions of membrane fluidity, recorded by steady-state fluorescence anisotropy of 1,6-di...

Benzyl alcohol (BA) is the most widely used antimicrobial preservative in multidose protein formulations, and has been shown to cause protein aggregation. Our previous work on a model protein cytochrome c demonstrated that this phenomenon occurs via partial unfolding. Here, we examine the validity of these results by investigating the effect of BA on a pharmaceutically relevant protein, interfe...

The influence of embryonic axis and exogenously applied plant growth hormones on protein mobilization and development of proteases have been investigated in Indian bean (Dolichos lablab L. var lignosus) seeds during germination and post-germinative growth up to 10 days. Accumulation of free amino acids synchronized with rapid proteolysis and higher levels were maintained throughout the germinat...

Purine-rich regions in DNA and RNA may contain both guanines and adenines, which have various biological functions. Here we report the crystal structure of an RNA purine-rich fragment containing both guanine and adenine at 1.4 A resolution. Adenines form an adenine tetrad in the N6-H em leader N7 conformation. Substitution of an adenine tetrad in the guanine tetraplex does not change the global...

Field trials with Dizigotheeca elegantissima were conducted at the experimental farm of Faculty of Agriculture, Azad University  Jiroft  in growth seasons of 2012 year. The aim of this work was to study the effect of foliar application of gibberellic acid [GA3] and benzyladenine [BA] at 0, 50, 100 and 150 mgL-1 on the vegetative growth and Photosynthetic pigments ...

Field trials with Spathiphyllum wallisii Regel were conducted at the experimental farm of Faculty of Agriculture, University Azad Jiroft in 2012 growth seasons. The aim of this work is to study the effect of foliar application with benzyladenine (BA) at 0, 100, 200 and 400 mg.L-1 and gibberellic acid (GA3) at 0, 100 and 200 mg.L-1 on the vegetative grow...

Field trials with Ficus benjamina L.were conducted at the experimental farm of Faculty of Agriculture, University Azad Jiroft in 2012 growth seasons. The aim of this work is to study the effect of foliar application with gibberellic acid (GA3) and benzyladenine (BA) at 0, 100 and 200 mg.L-1 on the vegetative growth and Photosynthetic pigments of Ficus benjamin...

Field trials with Spathiphyllum wallisii Regel were conducted at the experimental farm of Faculty of Agriculture, University Azad Jiroft in 2012 growth seasons. The aim of this work is to study the effect of foliar application with benzyladenine (BA) at 0, 100, 200 and 400 mg.L-1 and gibberellic acid (GA3) at 0, 100 and 200 mg.L-1 on the vegetative grow...

The asymmetric unit of the title co-crystal, C12H9N5O·0.5C6H10O4, consists of one mol-ecule of N (6)-benzoyl-adenine (BA) and one half-mol-ecule of adipic acid (AA), the other half being generated by inversion symmetry. The dihedral angle between the adenine and phenyl ring planes is 26.71 (7)°. The N (6)-benzoyl-adenine mol-ecule crystallizes in the N(7)-H tautomeric form with three non-proton...