Plant extracts are extensively researched as a source of green corrosion inhibitors. Herein, we report on a highly efficient and thermally stable corrosion inhibitor from the stem extract of high-altitude shrub Berberis aristata. The corrosion inhibition efficiency (IE) of the extract was tested in 1.0 M H2SO4 for the corrosion protection of mild steel (MS) by using gravimetric and electrochemi...

Berberine is a bioactive herbal ingredient isolated from the roots and bark of Berberis aristata or Coptis chinensis. To investigate the detailed pharmacokinetics of berberine and its mechanisms of hepatobiliary excretion, an in vivo microdialysis coupled with high-performance liquid chromatography was performed. In the control group, rats received berberine alone; in the drug-treated group, 10...

Drosophila melanogaster mutants with deficient kynurenine (KYN) formation from tryptophan (TRP) have longer life span than wild type flies. Administration of alpha-methyl-TRP and 5-methyl-TRY, the inhibitors of TRP-KYN metabolism, prolonged life span in wild-type flies. Both inhibitors are not available for human use. Berberine, an isoquinoline alkaloid isolated from Berberis aristata, is known...

BACKGROUND Suboptimal glycemic control is a common situation in diabetes, regardless of the wide range of drugs available to reach glycemic targets. Basic research in diabetes is endeavoring to identify new actives working as insulin savers, use of which could delay the introduction of injectable insulin or reduce the insulin dose needed. Commonly available as a nutraceutical, berberine is a po...

Ayurvedic system of medicine is using Berberis aristata and Curcuma longa herbs to treat different diseases including cancer. The study was performed to evaluate the synergetic anticancer activity of Berberine and Curcumin by estimating the inhibition of the cell proliferation by cytotoxicity assay using MTT method on specified human cell lines (A549, Hep-G2, MCF-7, Jurkat, and K562). All the c...

The present study describes the structural and floral composition of the vegetation of Sikre Village Development Committee (VDC) at Shivapuri National Park. Systematic sampling technique was used to analyze the vegetation of the forest. A quadrat size of 10mx10m was plotted at respective point for tree study and within 5mx5m plots for shrubs and 1mx1m for herbs analysis. The study recorded a to...

Inflammation is currently treated with NSAIDs. Unfortunately, these drugs increase the risk of blood clots, heart attacks, and strokes. Therefore, development potent anti-inflammatory from natural products being investigated. Natural made medicinal plants play an important role in curing many diseases associated inflammation. Conventional drug available market has various side effects. Because ...

Qualitative and quantitative data are presented for 21 collections of Berberis and one each of Epimedium, Jeffersonia, and Nandina. Most species of Berberis have large numbers of narrow vessels ~ixed with vasicentric tracheids. Scalariform perforation plates are reported here only for Epimedium, m wh1ch they are occasional. Berberidaceae have living fibers (Berberis), fiber-tracheids plus livin...