A new method for the separation of alkaline phosphatase isoenzymes by means of high performance liquid chromatography (HPLC) is presented. One isoenzyme was identified in homogenate of small intestine, two were identified in bone, and two in liver, and fragment and biliary isoenzymes were identified in bile. Sera from 32 patients with different diseases of the skeletal system or the liver were ...

Introduction Diseases aVecting the gall bladder and bile ducts occur commonly in the elderly. By the age of 70, cholelithiasis, the most frequently occurring disorder aVecting these organ systems, and its sequela, choledocholithiasis, are found in 33% of the population of the United States. The challenges facing the clinician responsible for treating elderly patients with biliary tract diseases...

Biliary epithelia express high levels of CD44 in hepatobiliary diseases. The role of CD44-hyaluronic acid interaction in biliary pathology, however, is unclear. A rat model of hepatic cholestasis induced by bile duct ligation was employed for characterization of hepatic CD44 expression and extracellular hyaluronan distribution. Cell culture experiments were employed to determine whether hyaluro...

AIM To evaluate the clinical value of various imageological methods in diagnosing the pancreato-biliary diseases and to seek the optimal procedure. METHODS Eighty-two cases of pancreato-biliary diseases confirmed by surgery and pathology were analyzed. There were 38 cases of cholelithiasis, 34 cases of pancreato-biliary tumors and 10 other cases. The imageological methods included B-US, CT, E...

Introduction MR cholangiopancreatography reveals the biliary system and the pancreatic duct noninvasively. Many reports on MR cholangiopancreatography have described usefulness of assessing benign or malignant biliary diseases, pancreatic diseases, or both biliary and pancreatic diseases using various imaging techniques including gradient-echo (i.e., steady-state free-precession sequence) [l] o...

OBJECTIVE To determine the pattern of liver diseases diagnosed in children at Ga-Rankuwa Hospital Histopathology Laboratory. DESIGN A retrospective study. SETTING Ga-Rankuwa Histopathology Laboratory. SUBJECTS Seventy two patients who underwent a liver biopsy during the study period. METHODS Laboratory records were reviewed and all liver biopsies were extracted. All slides were reviewed...

Endoscopic retrograde cholangiopancreatography (ERCP) was introduced over 4 decades ago. This challenging procedure has evolved significantly with experienced endoscopists performing this procedure safely and effectively with almost 100% biliary cannulation success rates. Since first used for biliary drainage in patients with choledocholithiasis, ERCP continues to play a critical role in the ma...

The authors are members of the professorial staff of the New York Post-graduate medical school, and their book is based on their experience with diseases of the biliary tract over a considerable period of time, especially at their hospital's clinic for the study of diseases of the liver and biliary tract. The preface promises a concise description of the latest concepts of the aetiology of dise...