نتایج جستجو برای: binding assays
تعداد نتایج: 511049 فیلتر نتایج به سال:
Sesquiterpene Lactones Modulated DNA Methylation through Inhibition of DNMTs in Ovarian Cancer Cells
Inappropriate DNA methylation of tumour suppressor genes can affect their expression and function, as such, has been a promising target for anti-cancer therapy. In gynaecological malignancy, ovarian cancer the highest associated rate mortality. This study investigated in vitro cytotoxicity four sesquiterpene lactones (SLs), including dehydroleucodine (Deh), alantolactone (Ala), costunolide (Cos...
Biofouling in the food industry is a huge issue, and one possible way to reduce surface fouling understand how naturally cleaning surfaces based on biomimetic designs influence bacterial binding. Four self-cleaning leaves (Tenderheart cabbage, Cauliflower, White cabbage Leek) were analysed for their properties artificial replicates produced. The subjected attachment, adhesion retention assays u...
Development of efficient peptide-based immunotherapy for shrimp allergy relies on the identification dominant T-cell epitopes its major allergen, tropomyosin. In this study, immunoinformatic tools, proliferation, cytokine release, IgG/IgE binding, and degranulation assays were used to identify characterize in Lit v 1 comparison with previously validated B-cell epitopes. The results showed that ...
Abstract Members of the pentatricopeptide repeat (PPR) protein family act as specificity factors in C-to-U RNA editing. The expansion PPR superfamily plants provides sequence variation required for design consensus-based RNA-binding proteins. We used this approach to a synthetic editing factor target one sites Arabidopsis chloroplast transcriptome recognised by natural CHLOROPLAST BIOGENESIS 19...
Probes for use in time-resolved fluorescence competitive binding assays at melanocortin receptors based on the parental ligands MSH(4), MSH(7), and NDP-α-MSH were prepared by solid phase synthesis methods, purified, and characterized. The saturation binding of these probes was studied using HEK-293 cells engineered to overexpress the human melanocortin 4 receptor (hMC4R) as well as the human ch...
Abstract Objective We investigated the discrepancy between clinical and PCR-based diagnosis of COVID-19. compared results ten patients with mild to severe Respiratory samples from all cases were tested on Roche SARS-CoV-2 (Cobas) assay, Filmarray RP2.1 (bioMereiux) TaqPath™ COVID19 (Thermofisher) PCR assays. Results Laboratory records COVID-19 examined. Initially, respiratory as negative ® assa...
Introduction The influenza virus genome consists of single-stranded RNAs and forms viral ribonucleoprotein (RNP) complexes. After replication in the nucleus, RNP interacts with protein M1. M1-viral complex is exported to cytoplasm via CRM1-dependent pathway using NS2/NEP as an export adaptor protein. NEP a 14 kDa diffusely localizes nucleus cytoplasm. Upon binding NLS motif M1, inhibits nuclear...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید