Sea urchin is one of the marine biotas that produce bioactive compounds and has biological activity, which antibacterial. This study aims to determine antibacterial activity crude extract D. setosum gonad its fractionation against test bacteria Staphylococcus aureus Escherichia coli conduct a zoochemical analysis content compounds. The used disc diffusion method while chemical was carried out q...

Kumis kucing (Orthosiphon stamineus) is a medicinal plant that can treat various diseases. has been known to contain bioactive compounds, namely polyphenol, alkaloid, and terpenoid which have antioxidant, antibacterial, antiviral, anti-inflammatory, anti-allergic anti-cancer activities. This study aims determine the phytochemical content, antioxidant activity, antibacterial activity of cat's wh...

Chemical analysis of the Mediterranean ascidian Polyandrocarpa zorritensis (Van Name 1931) resulted in the isolation of a series of molecules including two monoindole alkaloids, 3-indolylglyoxylic acid (3) and its methyl ester (4), 4-hydroxy-3-methoxyphenylglyoxylic acid methyl ester (1) and a new alkaloid we named zorrimidazolone (2). The structure of the novel compound 2 has been elucidated b...

Seeds of cumin (Cuminum cyminum L.) are widely used as a spice for their distinctive aroma. C. have been in traditional medicine to treat variety diseases. Literature presents ample evidence biomedical activities which is attributed its bioactive secondary metabolites - terpenes, phenols, and flavonoids. Besides, health effects seeds experimentally validated through phytochemical analysis depic...

Ergot alkaloids are nitrogen-containing natural products belonging to indole alkaloids. The best known producers are fungi of the phylum Ascomycota, e.g., Claviceps, Epichloë, Penicillium and Aspergillus species. According to their structures, ergot alkaloids can be divided into three groups: clavines, lysergic acid amides and peptides (ergopeptines). All of them share the first biosynthetic st...

Norcoclaurine synthase (NCS) is a Pictet-Spenglerase that catalyzes the first key step in plant benzylisoquinoline alkaloid metabolism, a compound family that includes bioactive natural products such as morphine. The enzyme has also shown great potential as a biocatalyst for the formation of chiral isoquinolines. Here we present new high-resolution X-ray crystallography data describing Thalictr...