The cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-clinical applications. This study was designed to evaluate and compare the cytotoxixity of two forms of bioactive glasses:nanopowder:andmicropowder. Human HGF1-PI53 gingival fibroblast cells were used to evaluate the cytotoxicity of 0.5, 1, 1.5, 2, 5, 10, 15 and 20 mg/mL concentrations of the two bioactive...

Thanks to their high biocompatibility and bioactivity, bioactive glasses are very promising materials for soft and hard tissue repair and engineering. Because bioactivity and specific surface area intrinsically linked, the last decade has seen a focus on the development of highly porous and/or nano-sized materials. This review emphasizes the synthesis of bioactive glass nanoparticles and materi...

Over the past decades, bioactive glass (BG) has been of a great interest in the bone regeneration field, due to its excellent biocompatibility, bioactivity and osteoconductivity. Herein, fabrication of bioactive glass as one-dimensional fibers by employing an Electrospinning process is reported. The Sol-Gel method was chosen considering the final fibers smoothness and homogeneity. Starting sol ...

Bioactive glasses prepared in SiO2–CaO–Na2O and P2O5 system are used as biomaterials in orthopaedic and maxillofacial surgery. Zn presents high physiological interest. It enhances physiological effects of implanted biomaterials. In this work, the thermal characteristics (Tg, Tc and Tf) of pure bioactive glass elaborated with different amounts of CaO, Na2O in pure glass and with different amount...

Highly porous bioactive glass-ceramic scaffolds were effectively fabricated by an inorganic gel casting technique, based on alkali activation and gelification, followed by viscous flow sintering. Glass powders, already known to yield a bioactive sintered glass-ceramic (CEL2) were dispersed in an alkaline solution, with partial dissolution of glass powders. The obtained glass suspensions underwe...

Bioactive glasses are able to bond to bone through the formation of hydroxy-carbonate apatite in body fluids while strontium (Sr)-releasing bioactive glasses are of interest for patients suffering from osteoporosis, as Sr was shown to increase bone formation both in vitro and in vivo. A melt-derived glass series (SiO(2)-P(2)O(5)-CaO-Na(2)O) with 0-100% of calcium (Ca) replaced by Sr on a molar ...

ARTICLE INFO Abstract Article History Received: 2 October 2014 Accepted: 2 January 2015 Bioactive glasses are silicate-based and can form a strong chemical bond with the tissues. These biomaterials are highly biocompatible and can form a hydroxyapatite layer when implanted in the body or soaked in the simulated body fluid. Due to several disadvantages, conventional glass processing method inclu...

This work investigated the effect of adding nanoparticulate (29 nm) bioactive glass particles on the bioactivity, degradation and in vitro cytocompatibility of poly(3-hydroxybutyrate) (P(3HB)) composites/nano-sized bioactive glass (n-BG). Two different concentrations (10 and 20 wt %) of nanoscale bioactive glass particles of 45S5 Bioglass composition were used to prepare composite films. Severa...

The bioactive glasses have been used in the medical field due to their wide spread benefits as implant coatings, bone substitutes and for treatment of dentine sensitivity. The purpose of this study was to incorporate zinc and fluoride in the bioactive glass for potential use in dentifrices as antibacterial and anticaries agents. A series of glass compositions based on SiO2, CaO, CaF2, MgO, and ...