dopaminergic signaling is one of the regulatory pathways being investigated for its implication in glucose metabolism. the aim of this study was to determine the effect of cabergoline on biochemical and anthropometric parameters in prediabetes stage (impaired fasting glucose and impaired glucose tolerance). in this double blind, placebo-controlled, pilot study, 27 prediabetic adults were random...

  Abstract   Background: Irregular Working hours, including night work and shift work, have been   found to be associated with alteration in various levels of biochemical factors. And some studies have showed association between shift work and blood biochemical disturbances in blood. In this epidemiological study we investigated, whether regular schedule of working hours can minimize the associ...

One hundred and five patients with rheumatoid arthritis treated with a variety of antirheumatic drugs, excepting glucocorticoids, were stratified according to the degree of functional impairment (functional classes I to IV) and duration of the disease (0-3 years; 4-8 years; and greater than 8 years). The variables investigated were distal forearm bone mineral content (BMC), biochemical markers ...

A genome-wide ethyl-N-nitrosourea (ENU) mutagenesis screen in mice was performed to identify novel regulators of erythropoiesis. Here, we describe a mouse line, RBC16, which harbours a dominantly inherited mutation in the Cpox gene, responsible for production of the haem biosynthesis enzyme, coproporphyrinogen III oxidase (CPOX). A premature stop codon in place of a tryptophan at amino acid 373...

Background: The aim of this study is to evaluate the effect 50 g oral glucose tolerance test (OGTT) on oxidative stress and interleukin-8 (IL-8) parameters in prediabetic pregnant women. Materials Methods: Fasting 1 hour blood samples were collected from 79 women who administered gr OGTT. Patients with a level 140–200 mg/dl considered as group. Thereafter, routine biochemical levels superoxide ...

BACKGROUND Polycystic ovarian syndrome (PCOS) is one of the most common endocrine conditions affecting women of reproductive age with a prevalence of approximately 5-10% worldwide. PCOS can be viewed as a heterogeneous androgen excess disorder with varying degrees of reproductive and metabolic abnormalities, whose diagnosis is based on anthropometric, biochemical and radiological abnormalities....

background: during the ramadan ceremony, adult muslims abstain from drinking and eating between sunrise and sunset. it seems influence on their lifestyle such as eating behavior, meal schedule and also their sleeping. these changes may effect on the endocrine and neuroendocrine circadian patterns and consequently on cardiovascular indices. this study was performed to assess the effects of ramad...

Introduction: Most cases of chronic diseases result in physical, psychological, financial, and social burdens on the patients and the economy. The overall health-related quality of life of patients can be positively influenced by several variables including glycemic control, economic status, comorbidities, presence of complications, and the quality of medical, psychological, and social support....

A broad spectrum of health benefits from intermittent fasting have been reported in studies on animal models and human subjects. However, the underlying mechanisms these beneficial effects remain largely elusive. The present study aimed to explore potential mode action mouse with a focus liver. C57BL/6 mice were subjected or ad libitum feeding as controls. It was determined that 12 h d...

Background: There is a lack of information regarding serum uric acid (SUA) and magnesium levels among the pre-diabetics population. This study aimed to assess biochemical assessment both in prediabetics Peshawar-KP region. Methodology: In this case-control study, patients having normal glucose were considered as control, cases. Fasting blood (FPG) between 100-125 mg/dl or HbA1c 5.7 6.4% pre-dia...