Concepts of biocompatibility have changed radically in recent years. This paper describes these new concepts and the present knowledge of the components and mediators of biocompatibility and leads to the development of a model for the explanation and rationalization of these phenomena. Of particular importance is the question of the assessment or evaluation of biocompatibility. The paper conclu...

The performance of an intraocular lens is determined by several factors such as the surgical technique, surgical complications, intraocular lens biomaterial and design, and host reaction to the lens. The factor indicating the biocompatibility of an intraocular lens is the behavior of inflammatory and lens epithelial cells. Hence, the biocompatibility of intraocular lens materials is assessed in...

Polymers are very versatile materials and are used in many applications including pharmaceutical applications. Natural polymers, modified natural polymers, and synthetic polymers are used as excipients in the manufacture of cosmetics and systems for conventional and modified delivery of drugs, by altering the composition and physical properties such as molecular weight, polydispersity, crystall...

Since decades, researchers are seeking novel therapeutic strategies to cure and monitor diseases for personalized health care needs. Numerous successful efforts are being made to design and develop personalized NanoMedicine approach to cure diseases at target site with minimum or no adverse effects. The designing of novel nanomaterials, maximum binding with therapeutic agent, controlled navigat...

BioIntraface®, Inc., located in Riverside, Rhode Island, was formed in February of 2009 to commercialize its biomaterials surface treatment technologies. The platform technologies involve the creation of economical, multifunctional metal oxide and polymer materials and coatings to control the bioactivity and antimicrobial properties of medical devices and implants. Biointraface® has continued o...

Methods Based on a computed tomography angiography of the aorta, we made a delrin ring, keeping the anatomical characteristics of the aortic annulus. A matrix one following we made from stainless steel with the shape of the three cusp aortic valve, followed by preparation of the injection of liquid polyurethane segmented (SPU), using a esterolitografia technique. In vitro tests: The materials u...

The first aim of this study was to evaluate the biocompatibility and degradation as well as potential clinical use of a new biodegradable PLGA (copolymer of L-lactide and glycolide acid) urethral stent with a braided mesh configuration. The second and at the same time, the main objective of this study was to develop a new drug-eluting biodegradable urethral stent. The biocompatibility profile o...

The study of nerve regeneration and functional recovery of the injured peripheral nerves represents a worldwide subject of clinical and scientific research. Our team aimed to obtain the first guide for nerve regeneration, bioartificial and biodegradable, using exclusively Romanian resources and having the advantages of price and quality, over the imported nerve conduits already used in clinical...