A method of introducing intrinsically photo luminescent properties to biodegradable polymer is introduced, exemplified by the synthesis of intrinsically photoluminescent polylactones that enable non-invasive monitoring and tracking of material degradation in vivo in realtime, as well as the formation of theranostic nanoparticles for cancer imaging and drug delivery.

This master’s thesis is a part of ‘Human Spare Parts’ research program by BioMediTech. The aim of the research program is to integrate different branches of biomedical engineering and stem cell research to discover new and better therapies and treatments. However, this thesis concentrates on biomaterials and sensor technology. The first part of the thesis, entitled the theoretical part is dedic...

BACKGROUND Biodegradable fixation systems could reduce/delete the problems associated with titanium plate removal. This means less surgical discomfort, and a reduction in costs. AIM The aim of the present study was to compare the cost-effectiveness between a biodegradable and a titanium system in Maxillofacial surgery. MATERIALS AND METHODS This multicenter RCT was performed in the Netherla...

Scaffolds have been utilized in tissue regeneration to facilitate the formation and maturation of new tissues or organs where a balance between temporary mechanical support and mass transport (degradation and cell growth) is ideally achieved. Polymers have been widely chosen as tissue scaffolding material having a good combination of biodegradability, biocompatibility, and porous structure. Met...

Drug delivery has become increasingly important mainly due to the awareness of the difficulties associated with a variety of old and new drugs. Of the many polymeric drug delivery systems, biodegradable polymers have been used widely as drug delivery systems because of their biocompatibility and biodegradability. The majority of biodegradable polymers have been used in the form of microparticle...

Polymer membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this review, various commercially available membranes are described. Much attention is paid to the recent development of biodegradable polymers applied in GTR and GBR, and the important issues of biodegradable polymeric membranes, including their classification, latest experimental...

We present a fabrication approach for the production of micromachined biodegradable microstructures, and illustrate its application in two areas: biodegradable microneedles for transdermal drug delivery, and biodegradable ratcheting surgical ties for blood vessel surgery. We fabricated solid polymer microneedles out of polyglycolide, polylactide and their copolymer using a micromolding techniqu...