OBJECTIVE To compare the probe detection method with the image quantification method when estimating (131)I biokinetics and radiation doses to the red marrow and whole body in the treatment of thyroid cancer patients. MATERIALS AND METHODS Fourteen patients with metastatic thyroid cancer, without metastatic bone involvement, were submitted to therapy planning in order to tailor the therapeuti...

The biokinetics of radon in the body has previously been studied with the assumption that its absorption through the skin is negligibly small. This assumption would be acceptable except in specific situations, such as bathing in a radon hot spring where the radon concentration in thermal water is far higher than that in air. The present study focused on such a situation in order to better under...

INTRODUCTION Radioimmunotherapy (RIT) with 90Y-labeled anti-CD66 antibody is used to selectively irradiate the red marrow (RM) before blood stem cell transplantation of acute leukemia patients. To calculate the activity to administer, time-integrated activity coefficients are required. These are estimated prior to therapy using gamma camera and serum measurements after injection of 111In labele...

A dynamic model that links biokinetics and consumer-resource dynamics for describing zinc (Zn) accumulation in abalone Haliotis diversicolor supertexta has been developed and then applied to Zn data from real abalone farms. The biokinetic parameters used in this study, uptake and depuration rate constants of abalone and their food source, red alga Gracilaria tenuistipitata var. liui, were obtai...

The bioluminescence activity and biokinetics of a recombinant Pseudomonas putida mt-2 were investigated in the presence various inducers: three chlorotoluenes (CTs) two nitrotoluenes (NTs). effects binary mixtures (40 combinations) eleven inducers on also studied. Different responses toxicities observed depending type concentrations. intensity bioluminescent response at 1 mM individual was foll...