polybrominated diphenyl ethers (pbdes) have been widely used in many products as flameretardants, which resulted in their release into the environment. little is known about the impact of coexisting pbdes on organisms. in this study, the in vivo effects of bde-47 and bde-99 on a suite of biomarkers, acetyl cholinesterase (ache), ethoxyresorufin-o-deethylase (erod), glutathione-s-transferase (gs...

background in the golestan cohort study that was launched to investigate the causes of esophageal cancer, a complete biospecimen bank was established for storage of collected blood, urine, hair, and nail samples. the objective of this study was to evaluate the feasibility of nail samples as a biomarker of selected trace elements status. methods thirty toenail samples were selected randomly from...

Background: Nowadays long non-coding RNAs are known as interesting functional part of the transcriptome. LncRNA SNHG6 was reported to be expressed more in breast cancer tissues than non-tumor ones. As a frequent cancer among women, breast cancer treatment needs applied biomarkers for fast prognosis and diagnosis. SNHG6 RNA and its splice variants could be considered as molecula...

"SLC2A4 Polymorphisms Can Be a New Molecular Biomarker for Sports Genomics" is an "Editorial Article" and hasn't abstract.

Background: This study has used biomarker of exposure-effect continuum to examine the biological characteristics of organophosphate (OP) toxicity and its genotoxic effect among rice farmers. Materials and Methods: A cross-sectional study was conducted among 160 pesticide exposed rice farmers and 160 adults from the fishing village as the unexposed group. They share the common socio-economical ...

Biomarker development is a common endeavor in medical research. The purpose to find indicators of disease occurrence or prognostic markers for response. process biomarkers often starts with showing mean differences between responders and non-responders those condition versus without. However, these statistically significant differences, while necessary are not sufficient validate biomarker. Sen...

Objective(s): In recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. We examined the practical applicability of the urinary levels of NAG (N-acetyl-β-D-glucosaminidase), AP (alkaline phosphatase), and LDH (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated wi...

This article examines the role of stratification of treatment assignment with regard to biomarker value in clinical trials that accept biomarker-positive and -negative patients but have a primary objective of evaluating treatment effect separately for the marker-positive subset. It also examines the issue of incomplete ascertainment of biomarker value and how this affects inference about treatm...