Plants with hypoglycemic properties are important in the treatment of diabetes. One of the mechanisms in reducing blood glucose is preventing the digestive absorption of glucose. The aim of this study was to evaluate the antioxidant properties of some traditional medicinal plants collected from different regions of Iran and their effects on glucose diffusion decrease. The amounts of phenolic co...

Introduction: Insulin resistance is the first stage of diabetes development. It has been defined as a dysmetabolic state in which biological response target tissues (particularly liver, muscle and adipose tissue) to circulating insulin impaired. This leads hyperinsulinemia, turn obesity type 2 (T2D). The basic ingredients Mediterranean diet, such fruit, vegetables, fish rich fat, extra virgin o...

In Peru and in the contemporary world, there are frequently acquired metabolic disorders such as type hypertension, obesity diabetes mellitus 2. Different studies point to new therapeutic routes that involve acquisition of healthy lifestyles an approach their diet. this way, have been numerous defend existence a relationship between consumption blueberries health recent years. perspective, rese...

The present study was conducted to test the effect of Origanum Majoranum Extract (OME) of leaves on alterations induced in a model of type 2 diabetic rats. Adult male Wistar rats were fed high fat diet for 3 weeks and injected a single dose of streptozotocin (35 mg/kg) intraperitoneally to induce type 2 diabetic rats. Diabetic rats were given aqueous extract of OME in a dose of 20 mg/kg orally ...

The present study was conducted to test the effect of Origanum Majoranum Extract (OME) of leaves on alterations induced in a model of type 2 diabetic rats. Adult male Wistar rats were fed high fat diet for 3 weeks and injected a single dose of streptozotocin (35 mg/kg) intraperitoneally to induce type 2 diabetic rats. Diabetic rats were given aqueous extract of OME in a dose of 20 mg/kg orally ...

miRNAs pose a good prospect in the diagnosis and treatment of type 2 diabetes (T2D). This study is aimed at investigating whether miR-720 targets Rab35 to regulate insulin secretion MIN6 cells its molecular mechanism clinical value as specific biomarker T2D. Fifty-five samples new T2D patients normal control were collected. Levels miR-720, fasting blood glucose, insulin, other indicators glucos...

Metabolism follows circadian rhythms, which are driven by peripheral clocks. Clock genes in the liver are entrained by daytime meals and food components. Proanthocyanidins (PAs), the most abundant flavonoids in the human diet, modulate lipid and glucose metabolism. The aim of this study was to determine whether PAs could adjust the clock system in the liver. Male Wistar rats were orally gavaged...

Morus nigra has been used popularly for several proposes, including diabetic. In an attempt to support medicinal value, the acute hypoglycemic, hypolipidemic, and antioxidant effects of the ethanolic extract of Morus nigra (EEMn 200 or 400 mg/kg b.w.) were evaluated in normal and alloxan-induced diabetic treated for 14 days. Serum biochemical and antioxidant analysis were performed at the end o...

Dietary flavonoids can improve endothelial function, but the response varies between individuals. Wide variability is also seen in flavonoid O-methylation, a major pathway of flavonoid metabolism. The O-methylation of flavonoids could alter activity, and thus influence any effect on endothelial function. The objective of the current analysis was to investigate whether variability in the endothe...

Introduction: Type 2 Diabetes mellitus (T2DM) is a heterogeneous disease which characterized by variable degrees of insulin resistance, impaired secretion and increased glucose production. Serum uric acid, an end product purine metabolism, has been shown to be associated with risk resistance components the metabolic syndrome in previous epidemiological studies. However, putative association ser...