نتایج جستجو برای: biomarker screening
تعداد نتایج: 282581 فیلتر نتایج به سال:
PURPOSE Cancer screening strategies have commonly adopted single-biomarker thresholds to identify abnormality. We investigated the impact of serial biomarker change interpreted through a risk algorithm on cancer detection rates. PATIENTS AND METHODS In the United Kingdom Collaborative Trial of Ovarian Cancer Screening, 46,237 women, age 50 years or older underwent incidence screening by using...
BACKGROUND The World Health Organization (WHO) has estimated that the number of cancer patients will increase by about 70% during the next 25 years world-wide. To deal with this problem, WHO has suggested a focus on prevention of tumor incidence and health screening for early detection of people with tumors. OBJECTIVE To investigate the use of thymidine kinase 1 (TK1), CEA and AFP in serum to...
Reducing the burden from death and suffering due to cancer requires improving prevention and treatment efforts and incorporating early detection and risk assessment strategies into clinical practice. Early detection and screening of cancer predates a formal cancer prevention intervention studies. For example, social scientists have been involved in research determining the epidemiologic basis o...
Point-of-care (POC) diagnostic platforms have the potential to enable low-cost, large-scale screening. As no single biomarker is shed by all ovarian cancers, multiplexed biomarker panels promise improved sensitivity and specificity to address the unmet need for early detection of ovarian cancer. We have configured the programmable bio-nano-chip (p-BNC)-a multiplexable, microfluidic, modular pla...
The principle reason for the examination article is to assess genoprotective action of herbal source leaves extract Indigofera tinctoria against insecticidal such as transfluthrin using Allium cepa a biomarker. has potential secondary metabolites, inorganic elements in phytochemical screening and different functional groups also. So that It possesses excellent anticancer, anti-inflammatory, ant...
objective(s): in recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. we examined the practical applicability of the urinary levels of nag (n-acetyl-β-d-glucosaminidase), ap (alkaline phosphatase), and ldh (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated wi...
There is a need for improved methods for detecting individuals at risk for cancer to target subsets of patients for more intensive individual screening and targeted cancer therapy and chemoprevention. One approach for accomplishing this objective is to detect premalignant molecular fingerprints in an organ at risk for cancer or to define biomarkers reflective of treatment selection and response...
abstract background: sp-a and sp-d are hydrophilic proteins which regulate the inflammatory response of the lung. pasteurella multocida is one of the most common bacteria isolated from calves suffering from shipping fever pneumonia, one of the most problems in dairy herds. objective: evaluation of surfactant content may provide a valuable diagnostic tool for detection of calf pneumonia due to p...
background: efficient screening for detection of colorectal cancer (crc) at earlier stages reduces its mortality. the purpose of this study was to investigate expression of carcinoembryonic antigen (cea) and human telomerase reverse transcriptase (htert) mrna in peripheral blood of crc patients and to present strategies for early detection screen test. methods: twenty seven patients in non-meta...
The establishment of high-throughput technologies has brought substantial advances to our understanding of the biology of many diseases at the molecular level and increasing expectations on the development of innovative molecularly targeted treatments and molecular biomarkers or diagnostic tests in the context of clinical studies. In this review article, we position the two critical statistical...
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