Obesity and overweight are among the major health problems in the world today. The excessive accumulation of fat in adipose tissue is accompanied by low‐grade inflamma‐ tion, adipokine secretion dysregulation, oxidative stress, and an alteration of the secretion of gut hormones and food intake related to peptides. This is related to the development of cardiovascular diseases, which have been in...

BACKGROUND The rodent carcinogen acrylamide was discovered in 2002 in commonly consumed foods. Epidemiologic studies have observed positive associations between acrylamide intake and endometrial, ovarian, and breast cancer risks, which suggest that acrylamide may have sex-hormonal effects. METHODS We cross-sectionally investigated the relationship between acrylamide intake and plasma levels o...

background nephrotic syndrome (ns) characterized by a large amounts of protein into urine and a set of indications that include: protein in urine, low blood protein levels, high cholesterol levels, high triglyceride levels, and swelling. therefore, aim of this study was to investigate the relationship between prognosis of nephrotic syndrome and blood biomarkers level in children of arak city, i...

background attention deficit hyperactivity disorder (adhd) is a multi-factorial disorder that has defined by hyperactivity, impulsivity and attention deficits. various neurotransmitters such as dopamine can play a role in its pathophysiology. the aim of this study was to examine the association of two common single nucleotide polymorphisms in drd2 gene, taq i a (t/c) and taq i b (g/a), with adh...

Copyright © 2008 Massachusetts Medical Society. Heart failure, a major and growing public health problem, appears to result not only from cardiac overload or injury but also from a complex interplay among genetic, neurohormonal, inflammatory, and biochemical changes acting on cardiac myocytes, the cardiac interstitium, or both. An increasing number of enzymes, hormones, biologic substances, and...

introduction: levofloxacin is one of the antibiotics with wide treatment application which is often applied for treating infections of genitourinary system and lower respiratory tract. noting that most antibiotics can affect the structure of ovary tissue, we have launched research into the effect of levofloxacin on hormone disorder resulting from tissue damage. methods: in this survey, 40 wista...

AIM There is paucity of research in the putative role of hormonal biomarkers in Attention Deficit Hyperactivity Disorder (ADHD). The current study aimed to analyze the clinical profile, socio-demographic status, co-morbidity, hormonal biomarkers namely Thyroid hormones and Cortisol in children with ADHD and compare them with healthy controls and to explore the association of the hormonal biomar...

Diagnostic accuracy can be improved considerably by combining multiple biomarkers. Although the likelihood ratio provides optimal solution to combination of biomarkers, the method is sensitive to distributional assumptions which are often difficult to justify. Alternatively simple linear combinations can be considered whose empirical solution may encounter intensive computation when the number ...