Background & aim: Congenital heart disease is one of the most common malformations at birth that require timely recognition and treatment. The aim of this study was to determine the prevalence and etiology of detected heart murmurs and association between congenital heart disease and heart murmurs. Recognition of murmurs etiology would help us to manage and treat them properly. Methods: In this...

Birth defects may influence the risk of childhood cancer development through a variety of mechanisms. The rarity of both birth defects and childhood cancers makes it challenging to study these associations, particularly for the very rare instances of each. To address this limitation, the authors conducted a record linkage-based cohort study among Texas children born between 1996 and 2005. Birth...

Birth defects may influence the risk of childhood cancer development through a variety of mechanisms. The rarity of both birth defects and childhood cancers makes it challenging to study these associations, particularly for the very rare instances of each. To address this limitation, the authors conducted a record linkage-based cohort study among Texas children born between 1996 and 2005. Birth...

Background: In the past 22 years, intracytoplasmic sperm injection (ICSI) on human oocytes become a successful method of treatment for most categories of infertility. But there are real concerns that possible malformations among ICSI infants are still not fully recognized. Despite the success of ICSI, the risk of major birth defects due to various parental factors or treatment may increase. We ...

Background: Down syndrome is the most common congenital chromosomal anomaly and occurs in about 1-10:1.000 live births globally. Various reports stated an increasing survival rate because of advanced medical surgical care. The highest mortality children takes place first three years life with its comorbidities being heart disease gastrointestinal defect. Low birth weight was also more compared ...

To cite: Sharma D, Yadav J, Garg E. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014203535 DESCRIPTION Case A male baby with birth weight of 3.2 kg was born to primi mother at term gestation. The baby had Apgar score of 7/8/8 and at birth was diagnosed to have microcephaly, cleft palate, single eye with absence of nose. On echo the baby had ventricular septal ...