نتایج جستجو برای: bisphosphonate

تعداد نتایج: 3890  

Journal: :Orthopedics 2009
Susan M Ott

Postmenopausal women with osteoporosis are commonly treated with the bisphosphonate class of medications, one of the most frequently prescribed medications in the United States. In the past 4 years, reports have been published implying that long-term bisphosphonate therapy could be linked to atraumatic femoral diaphyseal fractures. This article presents a case of a 67-year-old woman who present...

Journal: :Oncology nursing forum 2008
Margaret I Fitch Cathy Maxwell

PURPOSE/OBJECTIVES To describe the role of bisphosphonate therapy for metastatic bone disease and skeletal-related events associated with some of the most common malignancies, and to highlight the importance and untapped potential of nurses intervening in the education and treatment of patients with these issues. DATA SOURCES Contemporary evidence-based studies on the prevalence and impact on...

Journal: :Current opinion in environmental sustainability 2012
Anne Larigauderie Anne-Hélène Prieur-Richard Georgina M Mace Mark Lonsdale Harold A Mooney Lijbert Brussaard David Cooper Wolfgang Cramer Peter Daszak Sandra Díaz Anantha Duraiappah Thomas Elmqvist Daniel P Faith Louise E Jackson Cornelia Krug Paul W Leadley Philippe Le Prestre Hiroyuki Matsuda Margaret Palmer Charles Perrings Mirjam Pulleman Belinda Reyers Eugene A Rosa Robert J Scholes Eva Spehn Bl Turner Tetsukazu Yahara

DIVERSITAS, the international programme on biodiversity science, is releasing a strategic vision presenting scientific challenges for the next decade of research on biodiversity and ecosystem services: "Biodiversity and Ecosystem Services Science for a Sustainable Planet". This new vision is a response of the biodiversity and ecosystem services scientific community to the accelerating loss of t...

2017
Aasis Unnanuntana Panai Laohaprasitiporn Atthakorn Jarusriwanna

The appropriate time to initiate bisphosphonate treatment after a fragility fracture has not yet been established. In this study, we found no significant differences in short-term functional recovery between femoral neck fracture patients who received bisphosphonate treatment at 2 versus 12 weeks after hemiarthroplasty. INTRODUCTION Bisphosphonate is the mainstay therapy for prevention and tr...

Journal: :Organic & biomolecular chemistry 2012
Haoyue Xiang Xueyu Qi Yuyuan Xie Guangyu Xu Chunhao Yang

An efficient general synthetic approach has been developed to synthesize pyrazole-containing bisphosphonate (N-BPs) esters from chromenone derivatives via a sequential two-step reaction in one pot at ambient temperature in good to excellent yields. This protocol provides a new convenient method to prepare lipophilic bisphosphonate precursors with potential activities.

2015
T. Savaridas R. J. Wallace S. Dawson A. H. R. W. Simpson

Bone Joint Res 2015;4:99–104. Received 28 March 2014; Accepted after revision 01 April 2015 Objectives There remains conflicting evidence regarding cortical bone strength following bisphosphonate therapy. As part of a study to assess the effects of bisphosphonate treatment on the healing of rat tibial fractures, the mechanical properties and radiological density of the uninjured contralateral t...

2016
Yohei Sotsuka Toshihiro Fujiwara Kenichiro Kawai Soh Nishimoto Masao Kakibuchi

Recent reports have shown successful transfer of vascularized fibular flap in bisphosphonate-induced mandibular osteonecrosis. We present a case of a 50-year-old patient who presented with bisphosphonate-related osteonecrosis of bilateral maxilla, which is reconstructed using a fibular flap.

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009
Nimesh H Naik Thomas A Russo

The etiology of bisphosphonate-related osteonecrosis of the jaw is unknown but was initially postulated to be mediated by bisphosphonate accumulation within the jaws, resulting in avascular necrosis. Bisphosphonates may not be the primary cause. Actinomyces are an underrecognized agent in pathogenesis, and timely actinomycosis-specific treatment may improve outcome.

2013
Juan Erviti Álvaro Alonso Javier Gorricho Antonio López

OBJECTIVES To evaluate the association between the long-term use of bisphosphonates and the risk of hip fracture compared to never use among women aged 65 years or older. DESIGN Case-control study nested in a cohort. SETTING General practice research database operated by the Spanish Medicines Agency. PARTICIPANTS Cases of hip fracture were defined as women aged 65 years or older with a va...

Journal: :Journal of musculoskeletal & neuronal interactions 2013
V Patel L Graves B Lukert

Long term bisphosphonate use has been associated with "atypical" subtrochanteric and diaphyseal fractures of the femoral shaft. We are reporting a case of pelvic fractures in addition to atypical long bone fractures, in a patient with osteopenia treated with bisphosphonate for 8 years, and teriparatide for 2 years. After 5 years of bisphosphonate therapy the patient suffered an atraumatic fract...

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