BACKGROUND Dual antiplatelet treatment (DAPLT) for at least 12 months is recommended after drug eluting stent (DES) implantation, but concerns regarding the extended use of this treatment persist due to increased risk of bleeding. In this study are assessed the incidence, correlates, and clinical significance of bleeding complications in diabetic patients after long-term DAPLT post DES implanta...

OBJECTIVES Several endoscopic techniques have been proposed for the management of post-sphincterotomy bleeding. Lately, self-expandable metal stents deployment has gained popularity especially as a rescue therapy when other endoscopic techniques fail. METHODS-RESULTS We report the case report of a massive post-sphincterotomy bleeding in a patient with a self-expandable metal stent in the bili...

BACKGROUND Tranexamic acid (TXA) is an antifibrinolytic that inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. TXA has been used around the world to safely control bleeding since the 1960s. A large randomized trial recently conducted in >20,000 trauma patients adds to the large body of data documenting the useful...

OBJECTIVES Postcoital bleeding is an uncommon cause of gynecologic hemorrhage; however, it can be severe in a majority of cases necessitating surgical management. METHODS We report a case of severe postcoital bleeding in a young woman requiring blood transfusion. RESULTS Hemostasis was achieved using subselective embolization of cervical artery by metallic coils. CONCLUSION Our case demon...

Background. We aimed to evaluate the effectiveness of a suture-fixation mucopexy procedure by comparing with Doppler-guided hemorrhoidal artery ligation (DGHAL) in the management of patients with grade III hemorrhoids. Methods. This was a randomized controlled trial. One hundred patients with grade III hemorrhoids were randomly assigned to receive suture-fixation mucopexy (n = 50) or DGHAL (n =...

Dysfunctional Uterine Bleeding (DUB) is one of the most common and significant gynaecological complaints seen in about 10-15% of women attending a gynaecological clinic. DUB is excessive abnormal bleeding from the endometrium that is unrelated to any anatomic lesions of the genital tract. The largest incidence of DUB is in the women of the childbearing age group and menorrhagia was more common ...

OBJECTIVES Implanon was introduced in the UK in September 1999. We present here the results of our first 106 Implanon insertions, performed over a period of 18 months. The aims of the study were to study the clinical and demographic profile of Implanon users, to assess the continuation rates of Implanon in the local population, and to identify the reasons for removal. METHODS This was a case ...

KEY CLINICAL MESSAGE Acquired hemophilia A should be taken into account in the differential diagnosis of perioperative bleeding in patients without any apparent reason for activated partial thromboplastin time prolongation.

Approximately 20,000 adult and 25,000 paediatric tonsillectomies are performed each year in England. 0.9% of these patients return to theatre for post-tonsillectomy bleeding. The Royal College of Surgeons of England (RCSEng) have produced guidelines regarding emergency surgery, with standards for tonsillectomy discharge information. We audited our compliance with these guidelines and patient sa...

This article examines the early development of military rockets devised by the English inventor and Royal Society Fellow William Congreve in the first decade of the nineteenth century. Congreve’s efforts to imitate Indian war rockets used against the British in Mysore are set within a number of local and global contexts that saw increasing attempts by Europeans to imitate eastern pyrotechnics w...