BACKGROUND Intermittent negative pressure (INP) applied to the lower leg and foot increases foot perfusion in healthy volunteers. The aim of the present study was to describe the effects of INP to the lower leg and foot on foot macro- and microcirculation in patients with lower extremity peripheral arterial disease (PAD). METHODS In this experimental study, we analyzed foot circulation during...

BACKGROUND AND PURPOSE Computational fluid dynamics modeling is useful in the study of the hemodynamic environment of cerebral aneurysms, but patient-specific measurements of boundary conditions, such as blood flow velocity and pressure, have not been previously applied to the study of flow-diverting stents. We integrated patient-specific intravascular blood flow velocity and pressure measureme...

PURPOSE To conduct a validation study of a Doppler guide wire for potential neuroendovascular applications. METHODS A 12-MHz, 0.018-inch Doppler guide wire was evaluated in eight swine under various blood flow conditions using two types of in vivo cerebrovascular models (physiologic and arteriovenous shunting). Flow conditions were mechanically and pharmacologically altered. Doppler average p...

BACKGROUND Diabetes affects the vascular ocular circulation. Colour Doppler imaging allows for simultaneous two dimensional anatomical imaging and Doppler evaluation of blood flow velocity; with this technique ocular blood flow velocity can be evaluated in normal and diabetic patients. METHODS A prospective study compared blood flow velocity in ocular vessels (ophthalmic artery, posterior cil...

The relationship between the velocity of the cerebral circulation and the cerebral blood flow was explored at varying levels of PaCO(2), systemic arterial pressure, intracranial pressure, and perfusion pressure, using radioisotope techniques in baboons. Only at low flow rates did velocity increase with flow, and then non-linearly; at high rates velocity increased progressively less. Changes in ...

Knowledge concerning phasic coronary blood flow is based primarily on measurements obtained from epicardial coronary arteries, which, in part, function as capacitors. If present, epicardial capacitance effects could obscure the dynamic nature of phasic intramyocardial perfusion. To analyze this effect of epicardial capacitance, we simultaneously measured coronary blood flow velocity in an epica...

In this paper consider a two-fluid model consisting of a core region of suspension of all the erythrocytes (particles) in plasma (fluid) assumed to be a particle-fluid mixture and a peripheral layer of cell-free plasma (Newtonian fluid), has been proposed to represent blood flow in small diameter tubes with effects of magnetic. The analytical results obtained in the proposed model for effective...

We propose a saline injection-based method to quantify blood flow velocity in vivo with acoustic-resolution photoacoustic tomography. By monitoring the saline–blood interface propagating in the blood vessel, the flow velocity can be resolved. We first demonstrated our method in phantom experiments, where a root mean square error of prediction of 0.29  mm/s was achieved. By injecting saline into...