BACKGROUND Complement, activated during myocardial ischemia and reperfusion, causes myocardial damage through multiple processes. The COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) trial was performed to determine the effect of pexelizumab, a C5 complement inhibitor, on infarct size in patients with ST-segment-elevation myocardial infarction (MI) undergoing prim...

BACKGROUND The purpose of this study was to determine if persistent changes in the duration of bolus movement through the pharynx and bolus movement coordination with pharyngeal swallowing gestures occur after treatment of oropharyngeal carcinoma with chemoradiation therapy. METHODS The timing of bolus movement and coordination with swallowing gestures was evaluated in 30 patients using a mod...

BACKGROUND/AIMS Swallowing is a complex function with the control of the swallowing center being located in the brain stem. Our aim in this investigation was to evaluate, in healthy volunteers, the oral and pharyngeal transit of 2 bolus volumes and 2 consistencies, and the influence of these boluses on the proportion of pharyngeal clearance duration/hyoid movement duration. METHODS Videofluor...

To improve imaging quality and to reduce contrast dose and radiation exposure, an adaptive bolus chasing CT angiography was proposed so that the bolus peak position and the imaging aperture can be synchronized. The performance of the proposed adaptive bolus chasing CT angiography was experimentally evaluated based on the actual bolus dynamics. The experimental results show that the controlled t...

Introduction In electron beam therapy bolus is often used to conform as closely as possible to the target volume while avoiding critical structures in the depth. In most cases a flexible bolus can cover the skin without air gap. However, under certain conditions it is difficult –or even not possible– to avoid air gaps between bolus and patient without reducing treatment quality. In a special cl...

Background and Aims: During Cesarean section, hypotension occurs in the most of parturients, following spinal anesthesia. This prospective observational study was undertaken to determine efficacy two different Bolus Doses Phenylephrine for Prevention Spinal-Induced Hypotension during Section.
 Materials Methods: A total 120 parturients undergoing cesarean section were divided into groups g...

paper presents the work carried out in developing a precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dyn...

precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breath pattern analysis and statistical data re...