In the Results section under subheading 'Longitudinal in vivo assessment of biomaterial-induced bone formation' " Over the following 8 weeks the plural stayed closed. " should read: " Over the following 8 weeks the defects stayed closed ". Under subheading 'Temporal and spatial in vivo assessment of hydroxyapatite deposition during bone defect regeneration – anterior-posterior axis. ' " Thereaf...

OBJECTIVES To validate a critical-size mandibular bone defect model in miniature pigs. MATERIALS AND METHODS Bilateral notch defects were produced in the mandible of dentally mature miniature pigs. The right mandibular defect remained untreated while the left defect received an autograft. Bone healing was evaluated by computed tomography (CT) at 4 and 16 weeks, and by micro-CT and non-decalci...

Microradiography has been evaluated to measure bone healing into a 5.0mm outer diameter mandibular defect in the rat. This method provides high-resolution radiographs of the defects that can be used for an accurate measurement of bone defect healing. In 12 rats, the defect widths of 42-day-old mandibular defects have been measured both using microradiographs and histological sections. The defec...

Nanocrystalline hydroxyapatite (HA) has good biocompatibility and the potential to support bone formation. It represents a promising alternative to autologous bone grafting, which is considered the current gold standard for the treatment of low weight bearing bone defects. The purpose of this study was to compare three bone substitute pastes of different HA content and particle size with autolo...

BACKGROUND Although three-dimensional (3D) β-tricalcium phosphate (β-TCP) scaffolds serve as promising bone graft substitutes for the segmental bone defect treatment, no consensus has been achieved regarding their optimal 3D architecture. METHODS In this study, we has systematically compared four types of β-TCP bone graft substitutes with different 3D architectures, including two types of por...

BACKGROUND Endosseous dental implants with rough surfaces have been designed to improve early healing, especially in areas of poor bone or insufficient bone quantity. The aim of this study was to histomorphometrically assess the bone-to-implant contact on 3 different rough-surfaced implants following guided bone regeneration. METHODS Mandibular premolars and first molars were extracted in 12 ...

stafne bone cavities (sbcs) are uncommon well‑demarcated defects of the mandible, which often occur in the posterior portion of the jaw bone and are usually asymptomatic. furthermore, sbc is found in men aged 50–70‑year‑old. anterior mandibular variants of sbc are very rare. this article describes a case of anterior sbc in a 45‑year‑old man that resembled endodontic periapical lesions. upon his...

background cleft palate (cp) is a common congenital defect. it makes serious difficulties for cleft-affected children. the gold standard of care is autogenous bone grafting which may cause additional problems in donor site along with disappointing results. tissue engineering is a promising solution for a widespread range of defects and disorders. it is reasonable to utilize this novel technolog...