Non Hodgkin Lymphomas (NHL) are nodal or extra nodal monoclonal infiltrations by malignant lymphoid cells (B Lymphocytes in 80% of cases), which are distinguished as indolent or aggressive forms. According to the heterogeneity of lymphoid cells and their ubiquitous anatomical distribution, these disorders can develop in any organ and have very heterogeneous clinical expressions, but they are...

Background: Thrombocytopenia is commonly encountered in a wide range of haematological and non-haematological disorders. Bone marrow examination plays a major role in diagnosis. Aims: The aim of our study was to analyse the etiology and to study megakaryocytic series in different cases of thrombocytopenia, irrespective of age or sex. Methods: This prospective bone marrow aspiration study was do...

introduction: this review reports the current results of hematopoietic stem cell transplantation (hsct) in patients who had received transplantation in the hematology-oncology and sct research center, tehran, iran. methods: in iran, from 1991 through 2010, a total of 3170 hematopoietic stem cell transplantation have been carried out. the male/female patient ratio was 1909/1261 with a median age...

Hematological abnormalities are very common in the course of systemic lupus erythematosus (SLE). Myelofibrosis is a bone marrow disorder in which there is excessive fibrous tissue formation in the bone marrow. Various benign and malignant disorders can cause or be associated with a diffuse increase in the bone marrow reticular tissue. Some diseases such as infections, neoplasms, and autoimmune ...

it is estimated that annually 10 million people are affected by traumatic brain injury and it is one of the major causes of death and disability in accidents. studies have shown the potential therapeutic value of neural stem cell therapies. also, neural stem cell motility and migration to the site of injury has a great regeneration value of the damaged tissues. extracellular and intracellular f...

background: bone marrow-derived mesenchymal stem cells (bmmscs) transplantation has been considered as a promising milestone in liver fibrosis treatment. however, low amounts of homing are a major obstacle. we aimed to investigate the role of melatonin pretreatment in bmmsc homing into experimental liver fibrosis. methods: bmmscs were obtained, grown, propagated and preconditioned with 5 µm mel...

Background: The bone marrow examination is important for the investigation, diagnosis, and managementof blood, many systemic disorders. Morphological Bone alone issufficient to diagnose nutritional anemias most acute leukemia.This study aimed determine importance of morphological diagnosehematological non-hematological disorders like various illnesses that affect marrow.Methods: A prospective c...

In spite of the impressive advances in the area of molecular pathology, bone marrow morphology remains the diagnosis cornerstone to identify the various subtypes of myeloid neoplasms. Morphological examination of the bone marrow requires both bone marrow aspirate and bone marrow trephine biopsy. Immunohistochemistry of bone marrow biopsy with markers reactive in paraffin-embedded tissues repres...

BACKGROUND Bone marrow examination is regarded as one of the most important diagnostic procedure to assess various haematological disorders. The uses and advantages of bone marrow aspiration are numerous. This study was conducted with the aim to evaluate the frequency of involvement of bone marrow with malignant and non-malignant haematological and other clinical disorders and to observe the si...