A case report of histiocytosis X in a 2 years old in­faut, primarily admitted a for jaundice is discussed. Major clinical manifestations included: Jaundice, bi­lateral otitis media. pallor and loss of weight. Clinical examination revealed hepatosplenomegaly. lymphadenopathies and sever anemia. Seborrr.eic eruptions and ptechias appeared over the scalp and other parts of body surface a few days ...

Myeloid sarcoma is a tumor mass consisting of myeloid blasts, with or without maturation, occurring in an anatomical site other than bone marrow. More 2000 case reports so far, only few comprehensive studies have been done, which reflects the rarity and difficulties treatment this neoplasm. : A 17-year-old female presented complaints neck swelling since 2 months, breathlessness 5 days. PET CT- ...

objective(s):sea cucumber derived bioactive compound is considered efficient in treatment of bone disorders. this study was performed   to evaluate the effect of this extract on differentiation of rat bone marrow mesenchymal stem cells (rbmmsc) into osteogenic lineage. materials and methods: isolated rbmmsc were grown in dmem supplemented with 10% fbs. the cells were exposed to different concen...

background: langerhans' cell histiocytosis (lch) is a reactive proliferative disease of unknown pathogenesis characterized by proliferation of langerhans cells. involvement of bone marrow (bm), liver and lung are related to high risk factors and poor survival. the aim of this report is to highlight the clinical and haematological findings of 5 cases of lch with bm infiltration which may help to...

We present a description of the difficulties in diagnosing acute megakaryoblastic leukemia child with Down syndrome aggravated by multiple comorbidities. In this case, comprehensive assessment clinical data, results an automatic complete blood count detailed interpretation entire range parameters, as well morphological and immunophenotypic bone marrow examination using extended panel monoclonal...

Bone marrow is a complex organ containing undifferentiated cells from which the various constituents of blood originate. Under the control of hormones, cytokines and growth factors, normal marrow is susceptible to proliferation or suppression secondary to multiple influences, to include infection, medications, radiation, toxins, neoplasms, and nutritional deficiencies, among others. While histo...

We studied eight patients with miliary tuberculosis (TB). In all instances, tuberculomatous lesions were demonstrated in the aspirated bone marrow. We conclude that the bone marrow aspiration has great value in diagnosing miliary TB because it provides sufficient material to permit examination of serial sections as needed to confirm the diagnosis. The bone marrow aspiration also is safer than t...

Bone marrow transplantation might be an effective method to cure type 1 diabetes mellitus. This study aimed to investigate whether bone marrow transplantation could reverse hyperglycemia in diabetic mice and whether high-dose total body irradiation followed by high-dose bone marrow mononuclear cell infusion could improve the efficiency of bone marrow transplantation in treating diabetic mice. D...