We present a case of a scapular stress fracture in a 17-year-old athletic male that was initially thought to be a neoplasm. Radiographs showed a lesion at the neck of the glenoid with aggressive features. A subsequent MRI and bone scan supported a diagnosis of either tumor or infection. However, before a scheduled bone biopsy, a screening chest CT for pulmonary metastases revealed features of a...

Schwannoma is a benign nerve sheath neoplasm which mainly locates in the soft tissue but rarely originates in the bone. Intraosseous Schwannoma is prone to occur in the mandible and sacrum, while its occurrence is seldom seen in the calcaneus. Herein we report an 18-year-old man with a chief complaint of pain in the right heel. Radiographs revealed a huge, osteolytic, and expansile lesion with ...

Multilobular tumor of bone detected in a 2.5-year-old male Pekingese dog is reported. Grossly, the neoplasm consisted of multiple, variably sized, gritty, grayish-white to yellow nodules separated by thick collagenous septa. Histologically, these nodules contained multiple lobules of irregularly shaped and sized islands of well-differentiated osteoid and cartilage, separated by anastomosing fib...

Giant cell tumor (GCT) of bone is a giant-cell-rich bony lesion associated with abundant multinucleated osteoclast-type giant cells. It is a primary neoplasm of bone with characteristic clinical, radiological, and pathological features. It is an expansive and lytic lesion without periosteal reaction and prominent peripheral sclerosis. Giant cells are also seen in other diseases like giant cell ...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 73-year-old man presented with abdominal distension and general weakness for 3 weeks. One month prior to visit, brown-colored patchy skin lesion on left flank had appeared. Axillary lymph nodes were palpable on physical examination. Peripheral blood examin...

Langerhan's cell sarcoma (LCS) is a rare neoplasm with a poor prognosis. To our knowledge, only sixty-six cases have been published. We discuss two patients who presented very differently with LCS, as well as a recently published review of all sixty-six cases. Our first case had a complicated history of metastatic, high-grade myxofibrosarcomas and presented with a single skin lesion of LCS whic...

Desmoplastic fibroma (DF) is a benign, rare fibroblastic intraosseous neoplasm histologically resembling a desmoid soft tissue tumor. Although classified as benign, DF frequently exhibits an aggressive behavior, has a moderate-to-high recurrence rate, and often causes pathological fractures and extensive bone destruction. This case report presents an incidentally detected DF of the tibia, which...

Malignant epithelioid hemangioendothelioma (MEH), also known as high-risk epithelioid hemangioendothelioma, is a low- to intermediate-grade vascular malignancy originally described as a vascular neoplasm of endothelial origin. This very rare vascular neoplasm has been described mainly in soft tissue, but also in various organs and locations, including the liver, lung, brain, colon, lymph nodes,...

Giant cell tumor (GCT) is a benign primary bone neoplasm that usually occurre in the long bones. The skull is affected in only 1% of cases, predominantly in the sphenoid and temporal bones. Maxillary sinus involvement is exceedingly rare. The case is a 26 year-old man presented with history of gradually increasing swelling in the right side of face without any history of trauma or systemic diso...

Calcifying epithelial odontogenic tumor is a benign neoplasm, but its local destructive potential may lead to the formation of major bone defects. Microscopically, there are some histological variants. Among them, we highlight the clear cell variant due to its more aggressive behavior and a higher incidence of relapse. In this context, it is pertinent to describe the clear cell variant of calci...