Aim of this study was to evaluate by Micro-CT the structure of cancellous bone samples collected from historical human vertebrae of subjects affected by tuberculosis. Tuberculosis (TB) is a potentially fatal contagious disease most often caused by Mycobacterium tuberculosis but also by M. bovis and, although seldom, by other Mycobacterium species (M. aviumintracellulare, M. africanum). It mainl...

Skeletal tuberculosis is a well-known disease entity. We report the first case involving hyoid bone and the use of polymerase chain reaction-based test in detection and management. A 62-year-old male presented with neck swelling of a 20-day duration along with change of voice and dysphagia. Examination revealed a cystic, osteolytic lesion of the hyoid bone which histopathologically demonstrated...

Abdominal tuberculosis (TB) is the sixth commonest extra-pulmonary TB form after lymphatic, genitourinary, bone and joint, miliary and meningeal tuberculosis. Perforation is a serious and uncommon complication of abdominal tuberculosis which can occur even during the treatment. A 30-year-old man was admitted with a three-day history of abdominal pain who had emergency surgery for multiple perfo...

Herein we report a 6-year-old Afghans patient referred to Department of Dermatology, St. AL-Zahra Hospital in Isfahan with ulcerative and nodular lesions disseminated over the face, arms, buttocks, pelvic girdle and legs in 2002. Direct smears of the lesions were positive for Leishman bodies. Leishmanin skin test was negative. He also had dactylitis in some digits and toes. PCR from bone biopsy...

Tuberculosis osteomyelitis of foot bones is uncommon and may evade the diagnosis for long time because of atypical presentation, paucibacillary nature and relatively normal picture on laboratory investigations. As tuberculosis of bone mimic like chronic osteomyelitis, clinical picture with confection by other organism lead to misdiagnosis. A case of tubercular osteomyelitis of talus reported he...

Cutaneous tuberculosis, pulmonary tuberculosis and hanseniasis are all caused by different spp. of Mycobacterium, an intracellular pathogen whose development depends on impaired cell mediated immunity. Scrofuloderma is the most common variant of cutaneous tuberculosis, which is characterized by a direct extension of the skin which overlies the infected lymph gland, bone or joint, that breaks do...

3 Rady Children’s Hospital, UCSD, San Diego, CA Tuberculosis affects one third of the world’s population. While the disease may be adequately treated by chemotherapy, surgery plays an important role in the management of complications of the disease process. Tuberculosis is rare in the Western world, often leading to a delay in diagnosis and treatment. Our goal is to review the diagnosis and man...

During my early orthopaedic training, between 1936 and 1939, I failed to appreciate the full horror ofbone and joint tuberculosis, with its protracted treatment and crippling results; I encountered several cases during the war, but it was not until I became superintendent of the Derby County Tuberculosis and Orthopaedic Service in 1947 that this was borne in on me. The Orthopaedic Hospital at B...