Cost-effective, fibrinolytic agents possessing least or no antigenic properties are much in demand for their prospective use as clot busters in thrombolytic therapy. The present communication explores the potential of 22 endophytic Botryosphaeria species isolated from stem of Aegle marmelos for their fibrinolytic potential. Only nine fungal isolates exhibited proteolytic activity out of which o...

Since 1996, the primary objective of the New Crop Pathology Program at the University of the Free State has been to conduct a systematic survey of diseases occurring in cactus-pear [Opuntia ficus-indica (L.) Miller] orchards throughout the country and to investigate possible relationships between disease-causing microorganisms and various insects, specifically Drosophila sp. Numerous fungal gen...

Botryosphaeria rhodina (anamorph Lasiodiplodia theobromae) is a common endophyte and opportunistic pathogen on more than 500 tree species in the tropics and subtropics. During routine disease surveys of plantations in Australia and Venezuela several isolates differing from L. theobromae were identified and subsequently characterized based upon morphology and ITS and EF1-alpha nucleotide sequenc...

Endophytic fungus BS002 was isolated and characterized from Sophora flavescens by plate method, which has broad antimicrobial activity. Isolation and trace of a new bioactive compound from the fungus' culture extracts with the method of column chromatography and TLC biological autoradiography was conducted. Finally, it was identified as 6,7-(2'E) dibutenyl-5,8-dihydroxy-(Z)-cyclooct-2-ene-1,4-d...

A 12-yr study of fungi associated with Cannabis has revealed that many taxa cited in the Cannabis literature are based on misdeterminations or synonyms of species with wide host ranges (McPartland, 1992, 1994b, 1995b). New species have been discovered – Phomopsis ganjae (McPartland, 1983), Schiffnerula cannabis (McPartland&Hughes, 1994a), Fusicoccum marconii, Leptodothiorella marconii (McPartla...

A series of novel myrtenal derivatives bearing 1,2,4-triazole moiety were designed and synthesized by multi-step reactions in an attempt to develop potent antifungal agents. Their structures were confirmed by using UV-vis, FTIR, NMR, and ESI-MS analysis. Antifungal activity of the target compounds was preliminarily evaluated by the in vitro method against Fusarium oxysporum f. sp. cucumerinum, ...