Paradoxically, bovine cartilage stimulates the immune system in resisting cancer and viruses, but suppresses it in rheumatoid diseases. Thus it acts as a “normaliser”. According to Dr. Pridden, “bovine cartilage closely resembles foetal mesenchyme, the primordial tissue from which muscle, bone, tendons, ligaments, skin, fat and bone marrow (the heart of the immune system) all develop.” “The car...

AIM Realize the surgery of sinus lifting floor to allow the installation of osseointegrated implants for oral rehabilitation, with the combination of different biomaterials, autogenous bone and lyophilized bovine bone. BACKGROUND Oral rehabilitation using the installation of osseointegrated implants is an alternative surgical approach that results in the satisfactory form, function and esthet...

In Japan, the most common articular disease is knee osteoarthritis. Among many treatment methodologies, tissue engineering and regenerative medicine have recently received a lot of attention. In this field, cells and scaffolds are important, both ex vivo and in vivo. From the viewpoint of effective treatment, in addition to histological features, the compatibility of mechanical properties is al...

bovine inorganic biomaterials and correlate them with the dissolution rate. Bio-Oss®, GenoxInorgânico®, and Bonefill® were examined using field emission gun scanning electron microscopy (FEG-SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), specific surface area (BET), calcium/phosphorous molar ratio and a dissolution assay. Bio-Oss® showed a microand nanoporous str...

OBJECTIVE The purpose of this study was to histologically evaluate the effect of low-level laser (LLL) on the healing of critical size defects (CSD) in rat calvaria, filled with autogenous or inorganic bovine bone grafts. METHODS Sixty rats were divided into 6 groups (n = 10): C (control-filled with blood clot), LLL (low-level laser-GaAlAs, λ 780 nm, 100 mW, 210 J/cm(2), Φ 0.05 cm(2); 6 J/poi...

The objective of this proof-of-principle study was to examine the potential for improved bone regenerative outcomes in maxillary sinus augmentation procedures when recombinant human platelet-derived growth factor BB (0.3 mg/mL) is combined with particulate anorganic bovine bone mineral. The surgical outcomes in all treated sites were uneventful at 6 to 8 months, with sufficient regenerated bone...

Physiologic resorption due to remodeling processes affects autogenous corticocancellous grafts in the treatment of atrophic jawbone alveolar ridges. Such a situation in the past made overgrafting of the recipient site mandatory to get enough bone support to dental implants in order to perform a prosthetic rehabilitation. Anorganic bovine bone, conventionally used to treat alveolar bone deficien...

STATEMENT OF PROBLEM The use of the platelet concentration technique is widespread in dental implant surgery. However, its effect or mechanism is not clearly understood. PURPOSE This study introduced an animal model for the platelet concentration technique and evaluated its effect on bone formation with natural cancellous bovine bone mineral. MATERIAL AND METHODS Adult New Zealand white rab...

The combination of bone grafting materials with guided bone regeneration (GBR) membranes seems to provide promising results to restore bone defects in dental clinical practice. In the first part of this work, a novel protocol for decellularization and delipidation of bovine bone, based on multiple steps of thermal shock, washes with detergent and dehydration with alcohol, is described. This pro...

In order to understand the fracture mechanisms of bone subjected to external force well, an experimental study has been performed on the bovine bone by carrying out the three-point bending test with 3D digital image correlation (DIC) method, which provides a noncontact and full field of displacement measurement. The local strain and damage evolution of the bone has been recorded real time. The ...