Hand and foot movements are made more reliably when both limbs move in the same direction at the same time (isodirectional) compared with when they are made in opposite directions (anisodirectional). We hypothesized that M1 intracortical facilitation may subserve hand-foot coordination and reveal correlates that explain the preference for hand-foot movements to be performed in an isodirectional...

BACKGROUND AND PURPOSE The ability to live independently after stroke depends on the recovery of upper limb function. We hypothesized that bilateral priming with active-passive movements before upper limb physiotherapy would promote rebalancing of corticomotor excitability and would accelerate upper limb recovery at the subacute stage. METHODS A single-center randomized controlled trial of bi...

While most research on stopping action examines how an initiated response is stopped when a signal occurs (i.e., reactively), everyday life also calls for a mechanism to prepare to stop a particular response tendency (i.e., proactively and selectively). We hypothesized that human subjects can prepare to stop a particular response by proactively suppressing that response representation in the br...