BACKGROUND Neuropathological data are very scarce in systemic sclerosis and fail to demonstrate primary changes in the brains of such patients. CASE DESCRIPTIONS A 41-year-old woman with CREST syndrome developed signs of dementia after an episode of severe dehydration and died two months later of septic shock. A 63-year-old woman with CREST syndrome and a history of two unexplained transient ...

Influenza is occasionally complicated by CNS disorders, in particular impairment of consciousness. Severe disorders encompass multiple, distinct syndromes manifesting acute encephalopathy, whereas mild disorders represent multiple, ill-defined neuropsychiatric syndromes. Acute encephalopathy is manifested with seizures and coma, with or without multi-organ involvement. The outcome varies from d...

Abstract- Introduction   Hydatid cyst is endemic in India, with different clinical presentations as per site of involvement in body. Occurrence primarily in brain without involvement of other visceras is rare.   Case report   We present a case of eight year old female child with gradually progressive right hemiparesis and slurring of speech, with a large cyst in left cerebral hemisphere ...

Hyperexcitability pathologies, epitomized by epilepsy, are a largely unmet medical need, asking for conceptual developments on the functioning of networks of inter-communicating neurons and glia. Intercellular communication via gap junction (GJ) channels is largely present in mammalian brain. The GJ channels are made of proteins, essentially the connexins (Cxs) widely expressed in brain and in ...

introduction gradenigo’s syndrome consists of ophthalmoplegia, facial palsy, and facial pain due to involvement of abducens and facial nerves as well as the trigeminal ganglion. this involvement is due to infections of ipsilateral middle ear and mastoid bone. case presentation a 14-month-old girl was referred to a private clinic with chief complaint of acute and sudden-onset right ophthalmopleg...