acute dyspnea is a common cause of hospitalization in emergency departments (ed).distinguishing the cardiac causes of acute dyspnea from pulmonary ones is a major challenge for responsible physicians in eds. this study compares the characteristics of bedside ultrasonography with serum level of blood natriuretic peptide (bnp) in this regard. methods: this diagnostic accuracy study compares bedsi...

The human heart secretes both atrial natriuretic peptide and brain natriuretic peptide. This study attempts to clarify the pathophysiological significance of the peptides in cardiovascular diseases. Using immunoradiometric assay, plasma brain natriuretic peptide and atrial natriuretic peptide levels in essential hypertension, various secondary hypertension, chronic renal failure, chronic heart ...

sarily induce a large increase in left ventricular wall stress because of the obliterated left ventricular cavity in midto late systole as a result of hyperdynamic ejection. This reasoning was supported by micromanometer left ventricular and aortic pressure and flow measurements, but challenged by the outcome of myectomy surgery which resulted in significant improvement in symptoms and in radio...

OBJECTIVE The initial presentation of congenital and acquired heart disease in children can present a diagnostic challenge. We sought to evaluate B-type natriuretic peptide as a marker of critical heart disease in children at presentation in the acute care setting. METHODS A cohort of 33 pediatric patients with newly diagnosed congenital or acquired heart disease had B-type natriuretic peptid...

circulating levels of natriuretic peptides predict future cardiac event in patients with chronic hemodialysis. Nephron 2002;92:610–5. 14. Naganuma T, Sugimura K, Wada S, Yasumoto R, Sugimura T, Masuda C, et al. The prognostic role of brain natriuretic peptides in hemodialysis patients. Am J Nephrol 2002;22:437–44. 15. Parfrey PS. Cardiac disease in dialysis patients: diagnosis, burden of diseas...

introduction:the overlap syndrome, consisting ofobstructive sleep apnea hypopnea syndrome (osahs) and chronic obstructvie pulmonary disease (copd) is a major problem in copd patients. oshas corresponds to the likelihood of systemic hypertension.the present study was aimed to evaluate the association between apnea-hypopnea index and diastolic blood presssure (dbp) in overlap  patients. materials...

The diagnosis and treatment of dyspnea in the emergency department and in the prehospital setting is a challenge faced by the emergency physician and other prehospital care providers. While the use of lung ultrasound as a diagnostic tool in dyspneic patients has been well researched, there has been limited evaluation of its use in the prehospital setting. In the previous issue of Critical Care,...

Chronic obstructive pulmonary disease (COPD) is a complex disease with various phenotypes. The simultaneous determination of multiple biomarkers reflecting different pathobiological pathways could be useful in identifying individuals with an increased risk of death. We derived and validated a combination of three biomarkers (adrenomedullin, arginine vasopressin and atrial natriuretic peptide), ...

background chronic obstructive pulmonary disease (copd) is a devastating disease.while there is no cure for copd and the lung damage associated with this disease cannot be reversed, it is still very important to diagnose it as early as possible. objectives in this paper, we propose a novel method based on the measurement of air trapping in the lungs from ct images to detect copd and to evaluate...