Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

This study investigated the combined capability of thallium-201 (Tl)-SPECT and fluorine-18-fluoro-deoxy-glucose (FDG)-PET for differential diagnosis of posterior fossa brain tumors using multiple discriminant analysis.This retrospective study was conducted under approval of the institutional review board. In the hospital information system, 27 patients with posterior fossa intra-axial tumor bet...

in this study tsga10 has been demonstrated as a testis-specific human gene that encodes a protein localized in sperm-tail and conserved in ciliary structure. further investigations showed tsga10 signalling and expression during embryogenesis, brain development and some malignancies including brain tumors. given the role of this protein in neuronal development and in certain tumors, it could pot...

purpose: to report a case of unilateral severe visual loss and bilateral optic disc cupping secondary to brain metastasis of bronchogenic carcinoma patient and findings: a 48 year-old woman presented with severe visual loss of left eye without redness or pain or any systemic findings .clinical findings included decreased visual acuity of left eye to 4 m cf and (+3) positive marcus-gunn reflex ....

abstract the intraparenchymal schwannomas are very rare tumors with only 52 reported cases . we describe a 38 years old man with eight months history of poorly controlled seizures despite of medical therapy. on brain ct scan a 1.5 x 1.5 cm hypodense enhancing lesion was seen in right posterior-inferior frontal lobe. on brain mri the lesion was hypointense in t1 and hyperintense in t2 with homog...