Drs. Mouw and Harris have reviewed data from randomized clinical trials (RCTs) and from selected institutional experiences with whole breast irradiation (WBI), usually delivered with tangent pair radiation therapy (RT) over 5 to 7 weeks, accelerated whole-breast irradiation (AWBI), usually delivered over 3 to 4 weeks, and accelerated partial-breast irradiation (APBI), usually delivered in a sin...

Breast cancer is an important health problem that especially affects women. In breast where surgical procedures are the primary treatment modality, breast-conserving surgery with radiotherapy becoming more popular than mastectomy. Re-excision may be necessary in cases of recurrence or positive margins. Damage to cavity formed due scar formation old operation lodge make dissection difficult. Fai...

HYPOTHESIS Although postoperative fractionated radiotherapy (PFR) remains the standard method for conservative treatment of breast carcinomas, widespread experience in the use of full-dose intraoperative radiotherapy with electrons (ELIOT) merits its application in novel clinical situations, although long-term results of ongoing clinical trials have not been fully reported. DESIGN Retrospecti...

POLICY STATEMENT BlueCHiP for Medicare and Commercial Products: Breast Intensity-modulated radiotherapy (IMRT) may be considered medically necessary as a technique to deliver whole-breast irradiation in patients receiving treatment for left-sided breast cancer after breast conserving surgery, and for individuals with large breasts when treatment planning with 3-dimensional (3D) conformal result...

The National Institutes of Health Consensus Development Conference on Treatment of Early Stage Breast Cancer in 1990 indicated that breast conserving surgery with radiotherapy is the primary therapy for the majority of women with early stage breast cancer. Despite good aesthetic results, a remarkable number of patients suffer from lymphedema of the operated and irradiated breast. 131 study part...

AIMS To obtain a better understanding of the changes in radiotherapeutic management of breast cancer patients in the more developed areas of China over the past decade. METHODS Four academic radiation therapy departments located on the Southeast Coast of China were selected for the study. The survey was conducted on female breast cancer patients who received radiotherapy in 1999 and 2006. The...

BACKGROUND Randomized trials of radiotherapy and surgery for early breast cancer may have been too small to detect differences in long-term survival and recurrence reliably. We therefore performed a systematic overview (meta-analysis) of the results of such trials. METHODS Information was sought on each subject from investigators who conducted trials that began before 1985 and that compared l...

After breast-conserving treatment, the occurrence of ipsilateral breast tumor relapse raises the concern regarding whether it may represent two distinct types of lesion that it is important to define, a true recurrence (TR) or a new primary tumor (NPT). TR and NPT have different natural histories, prognosis, and in turn different implications for therapeutic management. We report the case of a ...

BACKGROUND Radiotherapy is an important treatment of choice for breast cancer patients after breast- conserving surgery, and we compare the feasibility of using dual arc volumetric modulated arc therapy (VMAT2), single arc volumetric modulated arc therapy (VMAT1) and Multi-beam Intensity Modulated Radiotherapy (M-IMRT) on patients after breast-conserving surgery. MATERIALS AND METHODS Thirty ...

Introduction: Breast conserving surgery with radiotherapy has replaced mastectomy as the standard care for earlystage breast cancer in the last few decades. Angiosarcoma (AS) arising in the irradiated breast after breastconserving therapy (BCT) is being reported in the literature with increasing frequency. In our study, we have reviewed cases of breast AS at our institution that have occurred i...