BACKGROUND Giant fibroadenoma of the breast is a rare benign breast tumour which seldom grows to a giant size, it is even rarer for this benign tumour to grow rapidly, ulcerate spontaneously and present like a fungating breast tumour in a way mimicking breast cancer. CASE PRESENTATION This is a presentation of a 14 year old premenarchal girl with a massive ulcerating and fungating left breast...

BACKGROUND The aim of this study was to investigate the association between LAPTM4B gene polymorphism and the risk of breast cancer among Egyptian female patients. Also, measurement was done of its serum level to evaluate its significance as a diagnostic marker for breast cancer. METHODS This case control study was done on 88 breast cancer patients, 40 with fibroadenoma and 80 healthy subject...

BACKGROUND Since mid 1990s video-assisted breast surgery (VABS) has been developed in the treatment of benign and malignant breast diseases. According to studies that are conducted mainly in Japan, this tehnique is safe, easy to learn and his main advantage is excellent cosmetic results on postoperative appearance of breasts that cannot be achived with standard surgical procedures. OBJECTIVE ...

BACKGROUND To evaluate the spectrum of breast diseases and their association with presenting complains of patients. METHODOLOGY It was a cross sectional study conducted from 1st January 2010 - 30th December 2012. A total of 254 breast specimens of patients, who were admitted in Civil Hospital Karachi with breast complaints, were included. Specimens were collected either from mastectomy, lumpe...

The aim of the present study was to assess the effect of the combined detection of serum vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) by Luminex multiplexed assays for the diagnosis, treatment and prognosis of breast cancer. Preoperative levels of serum VEGF and MMP-9 were detected via a lipid chip-based method in 301 breast cancer cases, 83 breast fibroadeno...

introduction giant fibroadenoma is a rare disease with unknown etiology. during pregnancy, fibroadenomas increase in size and may show lactational histologic changes. high concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. this may be a reason for the significant enlargement in this period. case presentation we presented...

UNLABELLED The presence of enlarged and pleomorphic nuclei is usually regarded as a feature of malignancy, but it may on occasion be seen in benign lesions such as mammary fibroadenomas. We present such a case of fibroadenoma occurring in a 37-year-old woman presenting with a self-palpable right breast mass. Histological examination of the tumor revealed the presence of multi and mononucleated ...

Introduction. The congenital anomalies of breast, especially the polymastia (supernumerary breast) and polythelia (supernumerary nipple), always do not fail to amuse the clinicians because of their varied presentations, associated renal anomalies, and pathologies arising from them. The axillary polymastia is a variant of ectopic breast tissue (EBT). Ectopic breast tissue can undergo the same ph...

Genesis of breast cancer is a multistage process involving accumulation of genetic alterations, but little is known about the implication of genetic alterations in benign breast disease (BBD) lesions. Among benign lesions of the breast, one of the most common is fibroadenoma. The relationship between fibroadenoma and breast cancer is not clear. Some epidemiological studies show an association w...

Background: Fibroepithelial tumors of the breast are a heterogeneous group biphasic lesions comprising an epithelial component and quantitatively predominant mesenchymal component. These classified into two major categories: Fibroadenoma phyllodes tumor (PT). Phyllodes benign, borderline malignant grade categories based on histological parameters.
 Methods: An analytical-cross sectional st...