Glucose-6-phosphate dehydrogenase deficiency is the most common enzymopathy worldwide. The precise prevalence of G6PD unknown in Burkina Faso. objective study was to describe difficulties diagnose this disease at Souro Sanou University hospital (CHUSS) Bobo-Dioulasso. It involved five patients comprising one child with homozygous SS sickle cell disease, adolescent screened following a family in...

bilateral pulmonary nodules. Histological examination of a biopsy sample of the thigh mass suggested synovial sarcoma. Because of the metastatic pulmonary lesions 150 mg doxorubicin was given by intravenous injection. Three days later the haemoglobin concentration fell suddenly to 10-6 g/dl (reticulocytes 4-1%'). Results of Coombs tests were negative. Supravital staining (cresyl blue) of a bloo...

In the present study, a novel catalytic-kinetic spectrophotometric method was developed for the determination of trace amounts of copper. It is based on the catalytic effect of Cu(II) on the reduction of brilliant cresyl blue (BCB) by ascorbic acid in pH 5.0 acetate buffer medium. The reaction was monitored spectrophotometrically by measuring the decrease in absorbance of BCB at 624 nm. The ope...

The covalent immobilization of synthetic or natural macromolecular compounds containing amino groups onto polystyrene (PS) solid surfaces is of great interest in diagnostic applications. A sensitive assay allowing the determination of reactive end groups is therefore a powerful tool for predicting the performance of the active surface. Recently, we reported the use of the Coomassie brilliant bl...

Previous studies have confirmed that oxidized adenosine triphosphate, a P2X7 receptor antagonist, attenuates lipopolysaccharide-mediated microglial activation and inflammatory expression following neuronal damage in rat brain. NaCl and temperature may affect the potency of oxidized adenosine triphosphate. Brilliant blue G is a derivative of a widely used food additive and has little toxicity. T...

The aim of the study is to analyze effect succinate-containing drugs on cellular composition blood in rats at rest, during free swimming and weight-loaded forced test.
 Materials Methods was carried out practically healthy sexually mature male Wistar (250–300 g). Animals received a drug (meso-2,3-dimercaptosuccinic acid) before (4 % body weight), after 12 hours exercise. Then, levels hemog...