Odour control from pig production facilities is a significant concern due to increased public awareness and the development of more stringent legislation to control production. Although many technologies exist, biofiltration is still the most attractive due to its low maintenance and operating costs. One of the key odour components, n-butyric acid, was selected for a laboratory scale biofilter ...

Clostridium tyrobutyricum is a gram-positive, rod-shaped, spore-forming, obligate anaerobic bacterium that produces butyric acid, acetic acid, hydrogen and carbon dioxide as its main fermentation products from various carbohydrates including glucose and xylose (Wu and Yang, 2003). Butyric acid is used to synthesize butyryl polymers in the chemical industry and to enhance butter-like note in foo...

The effect of short chain fatty acids (SCFAs) on gene expression in human, malignant cell lines was investigated, with a focus on signaling pathways. The commensal microbial flora produce high levels of SCFAs with established physiologic effects in humans. The most abundant SCFA metabolite in the human microflora is n-butyric acid. It is well known to activate endogenous latent Epstein-Barr vir...

In 1931 Klenk and Diebold (1) reported that sphingosine, upon oxidative degradation, gave rise to myristic acid and an optically active dihydroxyaminobutyric acid, [o(]A3 = 33.4”, which these authors characterized as an cY-amino-p ,r-dihydroxy-n-butyric acid. 5 years later Fischer and Feldmann (2), starting from D-glyceric aldehyde, synthesized an optically active oc-amino-p ,r-dihydroxy-n-buty...

Ferulic acid is released by microbial hydrolysis in the colon, where butyric acid, a major by-product of fermentation, constitutes the main energy source for colonic enterocytes. We investigated how varying concentrations of this short chain fatty acid may influence the absorption of the phenolic acid. Chronic treatment of Caco-2 cells with butyric acid resulted in increased mRNA and protein ab...

BACKGROUND Butyric acid as a renewable resource has become an increasingly attractive alternative to petroleum-based fuels. Clostridium tyrobutyricum ATCC 25755T is well documented as a fermentation strain for the production of acids. However, it has been reported that butyrate inhibits its growth, and the accumulation of acetate also inhibits biomass synthesis, making production of butyric aci...

[l-‘3C]Butyric acid and four different racemic 2-methylbutyric acids labeled with 13C or ‘H at various positions were synthesized to study the mechanism of 2ethylmalonic acid formation as well as several other steps of the R pathway of isoleucine metabolism in rats in uiuo. These are [2-‘HI-, [methyZ-‘3C]-, [methyl-‘HJ-, and 2-methyl[l-‘3C]butyric acid. These labeled precursors were administere...

Soil fungi that attacked methionine required a utilizable source of energy such as glucose for growth. This is an example of co-dissimilation. Experiments with one of the fungi, representative of the group, are reported. In the absence of glucose, pregrown mycelium, even when depleted of energy reserves, oxidatively deaminated methionine with accumulation of alpha-keto-gamma-methyl mercapto but...

Consumer interest in health-promoting food products is a major driving force for the increasing global demand of functional (probiotic) dairy foods. Yogurt is considered the ideal medium for delivery of beneficial functional ingredients. Gamma-amino-butyric acid has potential as a bioactive ingredient in functional foods due to its health-promoting properties as an anti-stress, anti-hypertensiv...

Ovarian cancer is the leading cause of death from gynaecological. There is an urgent need for testing novel tumour markers and therapeutic agents. HDAC inhibitors are a new class of target anticancer agents, which block deacetylation function, causing cell cycle arrest, differentiation and/or apoptosis. Vorinostat is an inhibitor of class I and II HDACs. Butyric acid is a small molecular weight...