The marine natural product malevamide D from the cyanobacterium Symploca hydnoides was synthesized for the first time. The final peptide coupling linked the dolaisoleuine and dolaproine subunits. The phenyl group of malevamide D was also functionalized with a photoreactive diazirine moiety, which was carried through seven reaction steps. Comprehensive assessment of the cytotoxicity in a panel o...

Hospice agencies provide comforting care and improved quality of life for terminally ill patients who choose to cease curative treatments. Hospice volunteers offer social, informational, and task-oriented support to hospice patients, families, and hospice workers. Law requires that hospice organizations receiving federal reimbursements must involve volunteers in at least 5% of overall patient c...

ABSTRACT- To investigate the effects of bio-chemical and organic fertilizers on yield and seeds NPK contents of pumpkin (Cucurbita pepo var. styriaca), an experiment was conducted at the Research Farm of Kurdistan University in 2009 growing season. Treatments were included 1) control, 2) seeds inoculated with free-living N fixing bacteria (NFB), 3) seeds inoculated with phosphate-solubilizing b...

BACKGROUND Vitamin C is an essential nutrient for maintaining human life. Vitamin C insufficiency in the plasma is closely related with the development of scurvy. However, in vivo kinetics of vitamin C regarding its storage and consumption is still largely unknown. METHODS We used Gulo(-/-) mice, which cannot synthesize vitamin C like human. Vitamin C level in plasma and organs from Gulo(-/-)...

Methane is a significant atmospheric trace gas in the context of greenhouse warming and climate change. The dominant sink of atmospheric methane is the hydroxyl radical (OH). Recently, a mechanism for production of chlorine radicals (Cl) in the marine boundary layer (MBL) via bromine autocatalysis has been proposed. The importance of this mechanism in producing a methane sink is not clear at pr...

Although vitamin C supplements were consumed for health maintenance and fatigue recovery, the effects of high doses of vitamin C supplement remains controversial. Our study performed the effects of 100 mg and 2,000 mg vitamin C supplements on plasma and urinary vitamin C concentration in Korean women. Twenty-four women completed the 4 weeks intervention. Anthropometric data, plasma and urinary ...