The polyisoprenols (PIs) dolichol and undecaprenol function as chemical carriers of glycosyl residues in the membrane-directed synthesis of glycoconjugates in prokaryotic and eukaryotic cells. The molecular details of how these lipid cofactors function is unknown. Presented here are results of deuterium NMR investigations of site specifically 2H-labeled PIs incorporated into model membranes. To...

The purposes of this research were to evaluate phorbol esters (PEs) degradation rate and enzyme production yield using submerged fermentation (SMF) as screening method and further using solid-state fermentation (SSF) as pilot scale-up study. SMF was carried out with 20 g seed cake in 100 ml minimal salt medium for 7 days incubation, while SSF was done with 20 g seed cake at 50% moisture content...

The data on heart disease patients obtained from the Ministry of Health Republic Indonesia in 2020 explains that has increased every year and ranks as highest cause death Indonesia, especially at productive ages. If people with are not treated properly, then their effective period a patient can experience more quickly. Thus, predictive model is able to help medical personnel solve health proble...

This paper evaluates the weak-form efficiency of the crude oil markets using the artificial neural network (ANN) model. Based on the daily historical data of the West Texas Intermediate (WTI) crude oil spot price over the period (02 January 198631 December 2013), the model was trained using backpropagation algorithm. The output of the neural network represents the predicted prices which are con...

A new high-speed pin-on-bar type tribometer has been developed to study the variation of friction coefficient with respect local thermomechanical contact conditions between tool and workpiece when drilling C45 steel. The forces temperatures are measured over a range pin indent depths sliding velocities in open closed loop tribo-systems. tribometer’s ability recreate is demonstrated induced surf...

In this paper we discuss several aspects of simulation based Bayesian econometric inference. We start at an elementary level on basic concepts of Bayesian analysis; evaluating integrals by simulation methods is a crucial ingredient in Bayesian inference. Next, the most popular and well-known simulation techniques are discussed, the Metropolis-Hastings algorithm and Gibbs sampling (being the mos...