نتایج جستجو برای: cadm

تعداد نتایج: 76  

Journal: :Modern rheumatology 2015
Yoshiro Horai Tomohiro Koga Keita Fujikawa Ayuko Takatani Ayako Nishino Yoshikazu Nakashima Takahisa Suzuki Shin-ya Kawashiri Naoki Iwamoto Kunihiro Ichinose Mami Tamai Hideki Nakamura Hiroaki Ida Tomoyuki Kakugawa Noriho Sakamoto Yuji Ishimatsu Hiroshi Mukae Yasuhito Hamaguchi Manabu Fujimoto Masataka Kuwana Tomoki Origuchi Shigeru Kohno Atsushi Kawakami

OBJECTIVE We have tried to clarify the clinical importance of the measurement of serum type-I interferon (IFN) in patients with anti-melanoma differentiation-associated gene 5 Ab (MDA5 Ab)-positive dermatomyositis (DM). METHODS We studied 30 patients with DM: 10 were anti-MDA5 Ab-positive and 20 were anti-MDA5 Ab-negative. At each patient's initial visit, serum IFN-α, IFN-β, interleukin 18 (I...

2016
Dong Jin Go Eun Young Lee Eun Bong Lee Yeong Wook Song Maximilian Ferdinand Konig Jin Kyun Park

Interstitial lung disease (ILD) is a major cause of death in patients with dermatomyositis (DM). This study was aimed to examine the utility of the erythrocyte sedimentation rate (ESR) as a predictor of ILD and prognostic marker of mortality in patients with DM. One hundred-and-fourteen patients with DM were examined, including 28 with clinically amyopathic DM (CADM). A diagnosis of ILD was mad...

2013
Bertha Maya Sopha

Although the paperless office (PLO) management system has been established with the goal of paper usage reduction, demand for paper has still showed an uptrend over the years. Given the substantial pressure on forest ecosystems due to a continued increase of paper consumption, understanding the behavioral aspects of paper consumption is, therefore, required. This present paper aims at exploring...

Journal: :European respiratory review : an official journal of the European Respiratory Society 2015
Morgane Gossez Marianne Levesque Chahéra Khouatra Vincent Cottin Lorna Garnier Nicole Fabien

Idiopathic inflammatory myopathies (IIMs) are characterised by inflammatory involvement of skeletal muscles causing weakness and pain, with possible associated systemic manifestations including frequent interstitial lung disease (ILD), and significant morbidity and mortality. Accumulating evidence suggests an important contribution of autoimmune responses to the pathogenesis of these diseases. ...

Journal: :The Journal of comparative neurology 2011
Paul R Hunter Nikolas Nikolaou Benjamin Odermatt Philip R Williams Uwe Drescher Martin P Meyer

Members of the Cadm/SynCAM/Necl/IGSF/TSLC family of cell adhesion molecules are known to have diverse functions during development of the nervous system, but information regarding their role during central nervous system (CNS) development in vivo is scarce. The rapid development of a relatively simple nervous system in larval zebrafish makes them a highly tractable model organism for studying g...

A fresh look at the system analysis helped us in finding a new way of calculating the risks associated with the system. The author found that, due to the shortcomings of RPN, more researches needed to be done in this area to use RPNs as a new source of information for system risk analysis. It is the purpose of this article to investigate the fundamental concepts of failure modes and effects ana...

Journal: :Acta dermato-venereologica 2014
Noriki Fujimoto Satoru Takayama Yasuhito Hamaguchi Manabu Fujimoto Toshihiro Tanaka

SHORT COMMUNICATION Pemphigus foliaceus (PF) is one of the autoimmune blistering diseases (ABDs) characterised by autoantibodies (Abs) binding to desmoglein (Dsg) 1, resulting in acant-holysis and intraepidermal blistering. Several other au-toimmune diseases have been reported to occur in patients with ABDs, such as rheumatoid arthritis, systemic lupus erythematosus, and Grave's disease (1). Ho...

2006
Poul Bjerregaard

Effect of selenium on uptake of cadmium in the benthic marine invertebrates Asterias rubens, Mytilus edulis, Littorina littorea, and Arenicola marina was investigated in a series of laboratory experiments. A. rubens exposed to 200 ~cg Cd 1-' alone took up cadmium in body wall, pyloric caeca, and tube feet at initial rates of 1 to 2 pg Cd g-' dry wt d-'; steady state concentrations of 10 to 30 p...

Journal: :Annals of the Rheumatic Diseases 2021

Background: Idiopathic inflammatory myopathies are a group of rare heterogeneous diseases that require multidisciplinary and standardized approach. Objectives: To clinically characterize patients with followed at an hospital’s Rheumatology Department, using the Rheumatic Diseases Portuguese Register (Reuma.pt). Methods: An observational transversal study was performed. Data on demographic varia...

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