Increases in osteoid volume with sodium fluoride, calcium, and vitamin D treatment are well documented. Small decreases in mineralisation rate have also been reported.2 But osteomalacia in the presence of high plasma 25-OHD concentrations has not been described in patients treated with this regimen. The plasma 1,25-(OH)2D3 concentration in our patient was just below the lower limit of normal, b...

Background & Aims: The present study compared fluoride uptake into enamel from sodium fluoride 0.05% gel and American Dental Association approved fluoride gel (Stannous fluoride 0.4% , Sultan Co.) when used on healthy enamel of the intact teeth. Methods: In an experimental study, 30 intact teeth extracted for orthodontic purposes were randomly assigned into two groups of 15 teeth. The teeth wer...

In previous studies of the reactions of fluoride ion with synthetic hydroxylapatite and powdered enamel and dentin (1,2), it was thought that low concentrations of fluoride ion might be affecting the rate of recrystallization of the apatites. Neuman et al. (3) found that fluoride impregnation had no effect on calcium and phosphate exchange of glycol-ashed bone. The experiments described below w...

This paper describes novel and innovative amorphous calcium magnesium fluoride phosphate (ACMFP) core-shell microparticles that may be applied in preventive dentistry for the prevention of caries treatment dentin hypersensitivity. The particles can synthesized with varied content, up to approximately 6 wt%, without any observable differences morphology or crystallinity. Fluoride release from is...

The aim of this in vitro study was to evaluate enamel microhardness following bleaching treatments using either high- or low-concentration hydrogen peroxide (HP) agents containing calcium and/or fluoride. Sixty enamel blocks were bleached with 1 of 6 different bleaching agents (n = 10). The high-concentration HP agents were Whiteness HP Maxx (35% HP), Whiteness HP Blue (35% HP, 2% calcium gluco...

OBJECTIVE To test whether slow-release sodium fluoride inhibits spinal fractures and is safe to use. DESIGN Placebo-controlled randomized trial. INTERVENTIONS Slow-release sodium fluoride, 25 mg twice daily, in four 14-month cycles (12 months receiving sodium fluoride followed by 2 months not receiving it) compared with placebo. Calcium citrate, 400 mg calcium twice daily, continuously in b...

Incubation of leaky or nonionic detergent-solubilized sarcoplasmic reticulum vesicles in solutions containing magnesium, beryllium, and fluoride caused a time-dependent complete inhibition of calcium ATPase activity. The inhibited state persisted through dialysis for 2 days versus EGTA and was reversed within minutes by the presence of 0.5 mM calcium. Calcium-independent ATPase activity was una...