A radio assay employing 14C-uridine to measure the intracellular killing of Candida albicans by phagocytes is presented. The principle of this new method is that after killing of Candida albicans by phagocytes RNA synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high CPM counts can be obtained within 135 min...

Background and Objectives: Candida species is one of the commensal microorganisms and a member of the oral cavity normal flora. In addition, Candida albicans is a microbiologic member of the oral cavity in children with dental caries. Currently, use of probiotics as a new biologic technique has attracted attention in order to prevent and control diseases. Enterococcus durans has shown useful an...

BACKGROUND Production of antibodies that are specific for allergens is an important pathological process in inflammatory allergic diseases. These contain the antibodies against antigens of Candida albicans, one of the normal microbial flora in an intestinal tract. We studied the effects of the prednisolone administration on the production of anti-Candida antibodies in the gastrointestinally C. ...

A laboratory experimental study conducted on antimicrobial effects of Coleus amboinicus, Lour folium Infusum towards Candida albicans and Streptococcus mutans (S. mutans). Effective concentration of Coleus amboinicus, Lour to decrease the quantities Candida albicans and S. mutans colonies is expected to be found out in this study. This study was using Coleus Amboinicus, Lour folium infusum with...

The aim of the present study was to determine in vitro phospholipase and protease activities in 122 Candida spp. isolated from several anatomically distinct sites of healthy adults. C. albicans (66.4%) was the most frequently isolated Candida spp. C. glabrata (7.3%), C. tropicalis (6.3%) and C. kefyr (4.9%) were the most frequently isolated non-C. albicans Candida spp. Fifty (40.9%) of the isol...

Candida albicans is an important opportunistic pathogen, causing both superficial mucosal infections and life-threatening systemic diseases in the clinic. The emergence of drug resistance in Candida albicans has become a noteworthy phenomenon due to the extensive use of antifungal agents and the development of biofilms. This study showed that budesonide potentiates the antifungal effect of fluc...

INTRODUCTION Urinary tract candidiasis is known as the most frequent nosocomial fungal infection worldwide. Candida albicans is the most common cause of nosocomial fungal urinary tract infections; however, a rapid change in the distribution of Candida species is undergoing. Simultaneously, the increase of urinary tract candidiasis has led to the appearance of antifungal resistant Candida specie...

BACKGROUND Opportunistic infections due to Candida species occur frequently in cancer patients because of their inherent immunosuppression. The aim of the present study was to investigate the epidemiology of yeast species from the oral cavity of patients during treatment for oncological and haematological malignancies. METHODS MALDI-TOF was performed to identify yeasts isolated from the oral ...