Adeno-associated virus (AAV) is one of the most promising gene transfer vector types featuring long-term expression and low toxicity. The lack pathogenicity availability many serotypes augmented applicability AAV virions in therapy applications. recombinant capsid includes therapeutic protein-coding transgene as well a promoter to initiate translation poly A sequence portion for stabilization. ...

Haemoglobin (Hb) abnormalities though quite frequent, are generally detected in populations during surveys and programmes run for prevention of Hb disorders. Several methods are now available for detection of Hb abnormalities. In this review, the following are discussed: (i) the methods used for characterization of haemoglobin disorders; (ii) the problems linked to diagnosis of thalassaemic tra...

The NISTmAb is a monoclonal antibody Reference Material from the National Institute of Standards and Technology; it is a class-representative IgG1κ intended serve as a pre-competitive platform for harmonization and technology development in the biopharmaceutical industry. The publication series of which this paper is a part describes NIST's overall control strategy to ensure NISTmAb quality and...