BACKGROUND Carcinoid tumors represent an unusual and complex disease spectrum with protean clinical manifestations. This compilation of several large United States-based databases comprising patients from 1950 to 1999 examines 13,715 carcinoid tumors and provides epidemiologic information regarding the natural history and evolution of the detection and diagnosis of this entity. METHODS The au...

Carcinoid tumors are rare, arising in 1.2-2.1 per 100,000 people in the general population per year.1 In 20%-30% of patients, the initial presentation occurs as a result of peptide production, ie, carcinoid syndrome. The malignant carcinoid syndrome consists of flushing, gastrointestinal hypermotility (secretory diarrhea), bronchospasm, and carcinoid heart disease. The syndrome is caused by the...

Metastasis to the breast is a rare occurrence, constituting fewer than 2% of all breast tumours. Of all metastatic tumours in the breast, most arise from contralateral breast primaries. Other reported primary solid tumour sites include melanoma; lung, gastric, and renal cancers; and approximately 29 cases of carcinoid tumour.Ambiguous presentations and an absence of carcinoid syndrome features ...

We have previously demonstrated that gastric and intestinal endocrine cell (End-cell) marker expression is important for assessment of the histogenesis of endocrine cell tumors. However, the End-cell phenotypes of carcinoid tumors in the rectum remain largely unclear. We therefore examined marker expression of rectal carcinoid tumors. We evaluated 20 rectal carcinoid tumors (as well as 8 from t...

Backgraund: Carcinoid tumor is the most common type of neuroendocrine tumor. Appendix is one of the most common sites of gastrointestinal carcinoid tumors. Appendectomy may be performed without mesoappendix excision by some surgeons in general practice. In that case, what happens, if a carcinoid tumor turns out to be responsible for the symptoms? In our series, this practice and carcinoid cases...

BACKGROUND Carcinoid involvement of left-sided heart valves has been reported in patients with a patent foramen ovale, carcinoid tumor of the lung, and active carcinoid syndrome with high levels of serotonin. The present study details the clinical features and surgical management of patients with carcinoid heart disease affecting both left- and right-sided valves. METHODS AND RESULTS Eleven p...

carcinoid tumor is a slow-growing type of neuroendocrine tumor, originating in the enterochromaffin cells and secreting mainly serotonin. the diagnosis is based on clinical symptoms, hormone levels, radiological and nuclear imaging, and histological confirmation. the clinical symptoms are characterized by flushing, diarrhea, abdominal pain, telangiectasia and/or bronchoconstriction. however, mo...

3Nielsen MS, Manners JM. Valve replacement in carcinoid syndrome. Anaesthesia 1979;34:494-9. 4Chatterjee K, Heather LC. Carcinoid heart disease from primary ovarian carcinoid tumors. Am Y Med 1968;45 :643-8. 5 Herreman F, Vernant P, Cachera JP, Monier Ph. Insuffisance tricuspidienne severe et tumeur carcin6ide primitive de l'ovaire. Succes du remplacement valvulaire a long terme. Arch Mal Coeur...

The author investigated clinicopathologic features of 13 cases of carcinoid tumor in the digestive organs. The 13 cases of carcinoid were identified from 18,267 pathological specimens of digestive organs in the last 10 years in our pathology laboratory. The tumor locations were rectum in 9 cases, duodenum in 2 cases, liver in 1 case, and stomach in 1 case. The age of the patients ranged from 52...

Thymic carcinoid tumors belong to the group of mediastinal tumors, but are quite rare and usually carry a very poor prognosis. This report illustrates a case in which a thymic carcinoid tumor that had led to cavernous sinus syndrome was treated successfully. This is the first case report of a thymic carcinoid to metastasize to the cavernous sinus.