We examined the morphology of the autonomic cardiac nervous system (ACNS) on 20 sides of 10 gibbons (Hylobatidae) of three genera, and we have inferred the evolution of the anatomy of the primate ACNS. We report the following. (1) Several trivial intraspecific and interspecific variations are present in gibbons, but the general arrangement of the ACNS in gibbons is consistent. (2) Although the ...

AIMS Cultured cardiac explants produce a heterogeneous population of cells including a distinctive population of refractile cells described here as small round cardiac explant derived cells (EDCs). The aim of this study was to explore the source, morphology and cardiogenic potential of EDCs. METHODS Transgenic MLC2v-Cre/ZEG, and actin-eGFP mice were used for lineage-tracing of EDCs in vitro a...

Atypical T wave morphology on scalar ECG may reflect abnormalities of the ventricular repolarization process but the link between these abnormalities and the occurrence of arrhythmic events is unclear. In this study, we investigated whether the occurrence of ventricular tachycardia (VT) in patients with dilated cardiomyopathy (DCM) have specific T wave morphology that may characterize their inc...

BACKGROUND Cardiac CT angiography (CCTA) has become an important adjunct in the structural assessment of the pulmonary veins (PV) prior to pulmonary vein isolation (PVI). Published data is conflicting regarding a relationship between left atrial appendage (LAA) and the risk of ischemic stroke (CVA) following PVI. We investigated the associations of volumetric and morphologic left atrial (LA) an...

patients and methods this retrospective study used a database of a cr ward of a hospital in iran. the demographic and clinical information of 574 patients participating in the cr program from april 2005 through april 2010 were analyzed. in order to determine the predictors of anxiety, binary logistic regression was performed. results after adjustment for gender, age and education, the results s...

Ca(+) influx to mitochondria is an important trigger for both mitochondrial dynamics and ATP generation in various cell types, including cardiac cells. Mitochondrial Ca(2+) influx is mainly mediated by the mitochondrial Ca(2+) uniporter (MCU). Growing evidence also indicates that mitochondrial Ca(2+) influx mechanisms are regulated not solely by MCU but also by multiple channels/transporters. W...

OBJECTIVES We investigated whether the presence of right ventricular (RV) abnormalities detected by cardiovascular magnetic resonance (CMR) predict adverse outcome in patients presenting with frequent premature ventricular complexes (PVCs) of left bundle branch block (LBBB) morphology. BACKGROUND CMR is a component of the diagnostic workup for the differential diagnosis between arrhythmogenic...

Developing organs acquire a specific three-dimensional form that ensures their normal function. Cardiac function, for example, depends upon properly shaped chambers that emerge from a primitive heart tube. The cellular mechanisms that control chamber shape are not yet understood. Here, we demonstrate that chamber morphology develops via changes in cell morphology, and we determine key regulator...

AIMS We assessed the changes in cardiac morphology between elite endurance-trained runners (n = 42) and elite sprinters (n = 34) over a 5-year period. In addition, we studied the relationship between heart size and maximum oxygen consumption (VO2 max). METHODS At the beginning of 5 consecutive seasons, all athletes underwent an incremental running test to determine VO2 max and a color-coded p...

Background Adverse outcomes are increasingly common in patients after the Fontan operation as they approach adulthood. Right ventricular (RV) morphology, ventricular dilation, and diminished ventricular strain have all been independently associated with death or heart transplant. The aim of this study was to assess the impact of ventricular morphology on ventricular stress/strain relationship i...